The Basics
What is Lurasidone?
Used to treat symptoms of mental disorders, such as schizophrenia, and may be used alone or with other medicines to treat depression caused by bipolar disorder.
Brand names for Lurasidone
Latuda
How Lurasidone is classified
Antipsychotic Agents
Lurasidone During Pregnancy
Lurasidone pregnancy category
Category BNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Lurasidone while pregnant
N/A
Taking Lurasidone While Breastfeeding
What are recommendations for lactation if you're taking Lurasidone?
Lurasidone is more than 99% bound to plasma proteins. so it is unlikely that the drug would be excreted into milk in sufficient amounts to affect a breastfed infant. But since there is no published experience with lurasidone during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.[1]
Maternal / infant drug levels
Lurasidone is more than 99% bound to plasma proteins. so it is unlikely that the drug would be excreted into milk in sufficient amounts to affect a breastfed infant. But since there is no published experience with lurasidone during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.[1]
Possible effects of Lurasidone on milk supply
Lurasidone has caused elevated prolactin serum in patients taking the drug.[2] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Possible alternatives to Lurasidone
Haloperidol, Olanzapine, Risperidone.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. McAllister-Williams RH, Baldwin DS, Cantwell R et al. British Association for Psychopharmacology consensus guidance on the use of psychotropic medication preconception, in pregnancy and postpartum 2017. J Psychopharmacol. 2017;31:519-52. PMID: 28440103
2. Anon. Latuda package insert. Sunovion Pharmaceuticals Inc. Ft. Lee, NJ. 2010.
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
