The Basics
What is Neratanib?
Neratinib is a tyrosine kinase inhibitor anticancer drug.
Brand names for Neratanib
Nerlynx
How Neratanib is classified
Antineoplastic Agents, Enzyme Inhibitors, Protein Kinase Inhibitors, Signal Transduction Inhibitors
Neratanib During Pregnancy
Neratanib pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Neratanib while pregnant
N/A
Taking Neratanib While Breastfeeding
What are recommendations for lactation if you're taking Neratanib?
No information is available on the clinical use of neratanib during breastfeeding. Because neratanib and its metabolite are over 99% bound to plasma proteins, the amount in milk is likely to be low. The manufacturer recommends that breastfeeding be discontinued during neratanib therapy.
Maternal / infant drug levels
No information is available on the clinical use of neratanib during breastfeeding. Because neratanib and its metabolite are over 99% bound to plasma proteins, the amount in milk is likely to be low. The manufacturer recommends that breastfeeding be discontinued during neratanib therapy.
Possible effects of Neratanib on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Neratanib
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
