The Basics
What is Norepinephrine?
Can treat low blood pressure and heart failure.
Brand names for Norepinephrine
Levophed
How Norepinephrine is classified
Adrenergic Agonists, Adrenergic Alpha-Agonists, Catecholamines, Sympathomimetics, Vasoconstrictor Agents
Norepinephrine During Pregnancy
Norepinephrine pregnancy category
Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Norepinephrine while pregnant
N/A
Taking Norepinephrine While Breastfeeding
What are recommendations for lactation if you're taking Norepinephrine?
No information is available on the use of norepinephrine during breastfeeding. Because of its poor oral bioavailability and short half-life, any norepinephrine in milk is unlikely to affect the infant. High intravenous doses of norepinephrine might reduce milk production or milk letdown.
Maternal / infant drug levels
No information is available on the use of norepinephrine during breastfeeding. Because of its poor oral bioavailability and short half-life, any norepinephrine in milk is unlikely to affect the infant. High intravenous doses of norepinephrine might reduce milk production or milk letdown.
Possible effects of Norepinephrine on milk supply
Relevant published information in nursing mothers was not found as of the revision date. Animal data indicate that norepinephrine can decrease serum prolactin and reduce milk production,[1] as well as inhibit the release of oxytocin, which inhibits milk ejection.[2]
Possible alternatives to Norepinephrine
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Thomas GB, Cummins JT, Doughton BW et al. Direct pituitary inhibition of prolactin secretion by dopamine and noradrenaline in sheep. J Endocrinol. 1989;123:393-402. PMID: 2607250
2. Song SL, Crowley WR, Grosvenor CE. Evidence for involvement of an adrenal catecholamine in the beta-adrenergic inhibition of oxytocin release in lactating rats. Brain Res. 1988;457:303-9. PMID: 2851365
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
