The Basics

What is Peppermint / Mentha x piperita?

Among the oldest herbs used for both culinary and medicinal products.

Brand names for Peppermint / Mentha x piperita

N/A

How Peppermint / Mentha x piperita is classified

Complementary Therapies, Food, Phytotherapy, Plants, Medicinal, Gastrointestinal Agents

Peppermint / Mentha x piperita During Pregnancy

Peppermint / Mentha x piperita pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Peppermint / Mentha x piperita while pregnant

N/A

Taking Peppermint / Mentha x piperita While Breastfeeding

What are recommendations for lactation if you're taking Peppermint / Mentha x piperita?

Peppermint (Mentha x piperita) contains menthol, menthone, menthyl acetate as major ingredients. Minor ingredients include 1,8-cineole, pulegone, bitter substances, caffeic acid, flavonoids, and tannins. Peppermint is a purported galactogogue; however, no scientifically valid clinical trials support this use.[1] Galactogogues should never replace evaluation and counseling on modifiable factors that affect milk production.[2] Topical peppermint gel and solutions have been studied for the prevention of pain and cracked nipples and areolas in nursing women. The peppermint preparations were more effective than placebo and expressed breastmilk, and about as effective as lanolin in some,[3][4][5][6] but not all studies.[7] A meta-analysis concluded that application of nothing or breastmilk may be superior to lanolin, but good studies are lacking.[8] Menthol and 1,-cineol are excreted into breastmilk in small quantities; the excretion of other components has not been studied. Peppermint is generally recognized as safe (GRAS) as a food by the U.S. Food and Drug Administration. Large doses can cause heartburn, nausea and vomiting. Allergic reactions, including headache, have been reported to menthol. If peppermint is used on the nipples, it should be used after nursing and wiped off before the next nursing. Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to prove the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does not certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products.

Maternal / infant drug levels

Peppermint (Mentha x piperita) contains menthol, menthone, menthyl acetate as major ingredients. Minor ingredients include 1,8-cineole, pulegone, bitter substances, caffeic acid, flavonoids, and tannins. Peppermint is a purported galactogogue; however, no scientifically valid clinical trials support this use.[1] Galactogogues should never replace evaluation and counseling on modifiable factors that affect milk production.[2] Topical peppermint gel and solutions have been studied for the prevention of pain and cracked nipples and areolas in nursing women. The peppermint preparations were more effective than placebo and expressed breastmilk, and about as effective as lanolin in some,[3][4][5][6] but not all studies.[7] A meta-analysis concluded that application of nothing or breastmilk may be superior to lanolin, but good studies are lacking.[8] Menthol and 1,-cineol are excreted into breastmilk in small quantities; the excretion of other components has not been studied. Peppermint is generally recognized as safe (GRAS) as a food by the U.S. Food and Drug Administration. Large doses can cause heartburn, nausea and vomiting. Allergic reactions, including headache, have been reported to menthol. If peppermint is used on the nipples, it should be used after nursing and wiped off before the next nursing. Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to prove the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does not certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products.

Possible effects of Peppermint / Mentha x piperita on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Peppermint / Mentha x piperita

None listed

List of References

Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Yarnell E. Botanical medicine in pregnancy and lactation. Altern Complement Ther. 1997;3 (April):93-100.
2. Brodribb W. ABM Clinical Protocol #9: Use of galactogogues in initiating or augmenting maternal milk production, second revision 2018. Breastfeed Med. 2018;13:307-14. PMID: 29902083
3. Sayyah Melli M, Rashidi MR, Delazar A et al. Effect of peppermint water on prevention of nipple cracks in lactating primiparous women: A randomized controlled trial. Int Breastfeed J. 2007;2:7. PMID: 17442122
4. Sayyah Melli M, Rashidi MR, Nokhoodchi A et al. A randomized trial of peppermint gel, lanolin ointment, and placebo gel to prevent nipple crack in primiparous breastfeeding women. Med Sci Monit. 2007;13:CR406-11. PMID: 17767120
5. Akbari SA, Alamolhoda SH, Baghban AA, Mirabi P. Effects of menthol essence and breast milk on the improvement of nipple fissures in breastfeeding women. J Res Med Sci. 2014;19:629-33. PMID: 25364362
6. Shanazi M, Farshbaf Khalili A, Kamalifard M et al. Comparison of the effects of lanolin, peppermint, and dexpanthenol creams on treatment of traumatic nipples in breastfeeding mothers. J Caring Sci. 2015;4:297-307. PMID: 26744729
7. Gharakhani Bahar T, Oshvandi K, Masoumi SZ et al. A comparative study of the effects of mint tea bag, mint cream, and breast milk on the treatment of cracked nipple in the lactation period: A randomized clinical trial study. Iran J Neonatol. 2018;9:72-9. DOI: doi:10.22038/ijn.2018.30078.1409
8. Dennis CL, Jackson K, Watson J. Interventions for treating painful nipples among breastfeeding women. Cochrane Database Syst Rev. 2014;12: CD007366. PMID: 25506813
9. Hausner H, Bredie WL, Molgaard C et al. Differential transfer of dietary flavour compounds into human breast milk. Physiol Behav. 2008;95:118-24. PMID: 18571209
10. Kirsch F, Beauchamp J, Buettner A. Time-dependent aroma changes in breast milk after oral intake of a pharmacological preparation containing 1,8-cineole. Clin Nutr. 2012;31:682-92. PMID: 22405404
11. Kirsch F, Buettner A. Characterisation of the metabolites of 1,8-cineole transferred into human milk: Concentrations and ratio of enantiomers. Metabolites. 2013;3:47-71. DOI: doi:10.3390/metabo3010047
12. Kirsch F, Horst K, Rohrig W et al. Tracing metabolite profiles in human milk: studies on the odorant 1,8-cineole transferred into breast milk after oral intake. Metabolomics. 2013;9:483-96. DOI: doi:10.1007/s11306-012-0466-9

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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