The Basics

What is Plazomicin?

An aminoglycoside antibiotic used to treat complicated urinary tract infections.

Brand names for Plazomicin

Zemdri

How Plazomicin is classified

Antibacterial Agents, Anti-Infective Agents, Aminoglycosides

Plazomicin During Pregnancy

Plazomicin pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Plazomicin while pregnant

N/A

Taking Plazomicin While Breastfeeding

What are recommendations for lactation if you're taking Plazomicin?

Plazomycin is an aminoglycoside antibiotic similar to gentamicin and amikacin. No information is available on the use of plazomycin during breastfeeding. However, based on the excretion of other aminoglycoside antibiotics, amounts in milk are expected to be low. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (e.g., thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis.

Maternal / infant drug levels

Plazomycin is an aminoglycoside antibiotic similar to gentamicin and amikacin. No information is available on the use of plazomycin during breastfeeding. However, based on the excretion of other aminoglycoside antibiotics, amounts in milk are expected to be low. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (e.g., thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis.

Possible effects of Plazomicin on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Plazomicin

None listed

List of References

Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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