The Basics
What is Pneumococcal Vaccines?
Helps protect against the 13 types of pneumococcal bacteria that most commonly cause serious infections.
Brand names for Pneumococcal Vaccines
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How Pneumococcal Vaccines is classified
Vaccines
Pneumococcal Vaccines During Pregnancy
Pneumococcal Vaccines pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Pneumococcal Vaccines while pregnant
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Taking Pneumococcal Vaccines While Breastfeeding
What are recommendations for lactation if you're taking Pneumococcal Vaccines?
The Centers for Disease Control and Prevention and several health professional organizations state that vaccines given to a nursing mother do not affect the safety of breastfeeding for mothers or infants and that breastfeeding is not a contraindication to pneumococcal vaccine. Immunization of the mother during the third trimester of pregnancy markedly increases the amount of pneumococcal antibodies in breastmilk.[1] Breastfed infants should be vaccinated according to the routine recommended schedules.[2][3][4]
Maternal / infant drug levels
The Centers for Disease Control and Prevention and several health professional organizations state that vaccines given to a nursing mother do not affect the safety of breastfeeding for mothers or infants and that breastfeeding is not a contraindication to pneumococcal vaccine. Immunization of the mother during the third trimester of pregnancy markedly increases the amount of pneumococcal antibodies in breastmilk.[1] Breastfed infants should be vaccinated according to the routine recommended schedules.[2][3][4]
Possible effects of Pneumococcal Vaccines on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Pneumococcal Vaccines
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Maertens K, De Schutter S, Braeckman T et al. Breastfeeding after maternal immunisation during pregnancy: Providing immunological protection to the newborn: A review. Vaccine. 2014;32:1786-92. PMID: 24530929
2. American Academy of Pediatrics Committee on Infectious Diseases, Kimberlin DW, Brady MT et al. Red Book: 2015 Report of the Committee on Infectious Diseases. 30th ed. Elk Grove Village, IL: American Academy of Pediatrics. 2015.
3. Gruslin A, Steben M, Halperin et al. Immunization in pregnancy: No. 220, December 2008. Int J Gynaecol Obstet. 2009;105:187-91. PMID: 19367691
4. General recommendations on immunization — recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2011;60 (RR-2):1-64. PMID: 21293327
5. Pabst HF. Immunomodulation by breast-feeding. Pediatr Infect Dis J. 1997;16:991-5. PMID: 9380478
6. Binks MJ, Moberley SA, Balloch A et al. Pneumum: Impact from a randomised controlled trial of maternal 23-valent pneumococcal polysaccharide vaccination on middle ear disease amongst indigenous infants, Northern Territory, Australia. Vaccine. 2015;33:6579-87. PMID: 26529076
7. Shahid NS, Steinhoff MC, Hoque SS et al. Serum, breast milk, and infant antibody after maternal immunisation with pneumococcal vaccine. Lancet. 1995;346:1252-7. PMID: 7475716
8. Munoz FM, Englund JA, Cheesman CC et al. Maternal immunization with pneumococcal polysaccharide vaccine in the thirdtrimester of gestation. Vaccine. 2002;20:826-37. PMID: 11738746
9. Finn A, Zhang Q, Seymour L et al. Induction of functional secretory IgA responses in breast milk, by pneumococcal capsular polysaccharides. J Infect Dis. 2002;186:1422-9. PMID: 12404157
10. Lehmann D, Pomat WS, Riley ID et al. Studies of maternal immunisation with pneumococcal polysaccharide vaccine in Papua New Guinea. Vaccine. 2003;21:3446-50. PMID: 12850357
11. Obaro SK, Deubzer HE, Newman VO et al. Serotype-specific pneumococcal antibodies in breast milk of Gambian women immunized with a pneumococcal polysaccharide vaccine during pregnancy. Pediatr Infect Dis J. 2004;23:1023-9. PMID: 15545857
12. Deubzer HE, Obaro SK, Newman VO et al. Colostrum obtained from women vaccinated with pneumococcal vaccine during pregnancy inhibits epithelial adhesion of Streptococcus pneumoniae. J Infect Dis. 2004;190:1758-61. PMID: 15499530
13. Silfverdal SA, Ekholm L, Bodin L. Breastfeeding enhances the antibody response to Hib and pneumococcal serotype 6B and 14 after vaccination with conjugate vaccines. Vaccine. 2007;25:1497-502. PMID: 17097198
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
