The Basics
What is Prucalopride?
Given to people who have chronic constipation for whom laxatives do not provide adequate relief.
Brand names for Prucalopride
Motegrity
How Prucalopride is classified
Gastrointestinal Agents, Laxatives, Serotonin 5-HT4 Receptor Agonists
Prucalopride During Pregnancy
Prucalopride pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Prucalopride while pregnant
N/A
Taking Prucalopride While Breastfeeding
What are recommendations for lactation if you're taking Prucalopride?
No published experience exists with prucalopride during breastfeeding. However, the manufacturer reports an unpublished study that indicates a relatively low amount of drug in breastmilk. Until more data become available, monitor the breastfed infant for diarrhea.
Maternal / infant drug levels
No published experience exists with prucalopride during breastfeeding. However, the manufacturer reports an unpublished study that indicates a relatively low amount of drug in breastmilk. Until more data become available, monitor the breastfed infant for diarrhea.
Possible effects of Prucalopride on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Prucalopride
Linaclotide, Lubiprostone, Plecanatide, Psyllium.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
