Quniupristin-Dalfopristin

The Basics

What is Quniupristin-Dalfopristin?

combination of two antibiotics used to treat infections by staphylococci and by vancomycin-resistant Enterococcus faecium

Brand names for Quniupristin-Dalfopristin

Synercid

How Quniupristin-Dalfopristin is classified

Anti-Bacterial Agents, Anti-Infective Agents, Protein Synthesis Inhibitors

Quniupristin-Dalfopristin During Pregnancy

Quniupristin-Dalfopristin pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Quniupristin-Dalfopristin while pregnant

N/A

Taking Quniupristin-Dalfopristin While Breastfeeding

What are recommendations for lactation if you're taking Quniupristin-Dalfopristin?

Quinupristin and dalfopristin are relatively large molecules that are unlikely to be excreted into breastmilk in large amounts or to be absorbed orally by the breastfeeding infant.[1] However, since no information is available on the use of quinupristin and dalfopristin during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Maternal / infant drug levels

Quinupristin and dalfopristin are relatively large molecules that are unlikely to be excreted into breastmilk in large amounts or to be absorbed orally by the breastfeeding infant.[1] However, since no information is available on the use of quinupristin and dalfopristin during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Possible effects of Quniupristin-Dalfopristin on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Quniupristin-Dalfopristin

Clindamycin, Doxycycline, Linezolid, Trimethoprim-Sulfamethoxazole,Vancomycin.