The Basics

What is Rhenium-186 HEDP?

Widely used for palliative treatment of bone metastases originating from breast or prostate cancer.

Brand names for Rhenium-186 HEDP

Na

How Rhenium-186 HEDP is classified

Radiopharmaceuticals, Etidronic Acid

Rhenium-186 HEDP During Pregnancy

Rhenium-186 HEDP pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Rhenium-186 HEDP while pregnant

N/A

Taking Rhenium-186 HEDP While Breastfeeding

What are recommendations for lactation if you're taking Rhenium-186 HEDP?

Information in this record refers to the use of rhenium-186 HEDP (rhenium-186 etidronate) as a therapeutic agent. No information is available on the therapeutic use of rhenium HEDP during breastfeeding. Because strontium can substitute for calcium in infant bones, the manufacturer and expert opinion recommend discontinuing breastfeeding before a nursing mother receives rhenium HEDP.[1]

Maternal / infant drug levels

Information in this record refers to the use of rhenium-186 HEDP (rhenium-186 etidronate) as a therapeutic agent. No information is available on the therapeutic use of rhenium HEDP during breastfeeding. Because strontium can substitute for calcium in infant bones, the manufacturer and expert opinion recommend discontinuing breastfeeding before a nursing mother receives rhenium HEDP.[1]

Possible effects of Rhenium-186 HEDP on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Rhenium-186 HEDP

None listed

List of References

Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Bodei L, Lam M, Chiesa C et al. EANM procedure guideline for treatment of refractory metastatic bone pain. Eur J Nucl Med Mol Imaging. 2008;35:1934-40. PMID: 18649080

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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