The Basics
What is Safinamide?
Used as an add-on treatment for Parkinson’s disease during off episodes.
Brand names for Safinamide
Xadago
How Safinamide is classified
Antiparkinson Agents, Monoamine Oxidase Inhibitors
Safinamide During Pregnancy
Safinamide pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Safinamide while pregnant
N/A
Taking Safinamide While Breastfeeding
What are recommendations for lactation if you're taking Safinamide?
No information is available on the use of safinamide during breastfeeding. Because of liver toxicity in nursing rat pups, the manufacturer recommends that the drug not be used in nursing mothers. Alternate agents are preferred.
Maternal / infant drug levels
No information is available on the use of safinamide during breastfeeding. Because of liver toxicity in nursing rat pups, the manufacturer recommends that the drug not be used in nursing mothers. Alternate agents are preferred.
Possible effects of Safinamide on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Safinamide
Selegiline.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.