The Basics

What is Sage / Salvia officinalis?

Has been used to treat mild dyspepsia (such as heartburn and bloating), excessive sweating, age-related cognitive disorders, and inflammations in the throat and skin.

Brand names for Sage / Salvia officinalis

Na

How Sage / Salvia officinalis is classified

Complementary Therapies, Phytotherapy, Plants, Medicinal

Sage / Salvia officinalis During Pregnancy

Sage / Salvia officinalis pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Sage / Salvia officinalis while pregnant

N/A

Taking Sage / Salvia officinalis While Breastfeeding

What are recommendations for lactation if you're taking Sage / Salvia officinalis?

Sage (Salvia officinalis) leaf contains tannins (salviatannin), essential oils (including alpha-thujone, beta-thujone, 1,8 cineole, and camphor), flavones, phenolic acids, phenylpropanoid glycosides, triterpenoids, and diterpenes. Spanish sage (Salvia lavandulaefolia) is a related species with similar components, although its thujone content is lower. Sage is often misidentified and adulterated; Salvia bertolonii or Salvia pratensis are sometimes used in instead of Salvia officinalis or as an adulterant. Sage purportedly reduces lactation and has been used to aid with weaning or an overabundant milk supply;[1][2][3][4] however, no scientific studies could be located that evaluate the effect of sage on the milk supply. No data exist on the safety of sage in nursing mothers or infants. In general, sage is well tolerated, with occasional nausea, vomiting, abdominal pain, dizziness, agitation, and wheezing. Thujone and camphor are both neurotoxic in high doses. Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to prove the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does not certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products.

Maternal / infant drug levels

Sage (Salvia officinalis) leaf contains tannins (salviatannin), essential oils (including alpha-thujone, beta-thujone, 1,8 cineole, and camphor), flavones, phenolic acids, phenylpropanoid glycosides, triterpenoids, and diterpenes. Spanish sage (Salvia lavandulaefolia) is a related species with similar components, although its thujone content is lower. Sage is often misidentified and adulterated; Salvia bertolonii or Salvia pratensis are sometimes used in instead of Salvia officinalis or as an adulterant. Sage purportedly reduces lactation and has been used to aid with weaning or an overabundant milk supply;[1][2][3][4] however, no scientific studies could be located that evaluate the effect of sage on the milk supply. No data exist on the safety of sage in nursing mothers or infants. In general, sage is well tolerated, with occasional nausea, vomiting, abdominal pain, dizziness, agitation, and wheezing. Thujone and camphor are both neurotoxic in high doses. Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to prove the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does not certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products.

Possible effects of Sage / Salvia officinalis on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Sage / Salvia officinalis

List of References

Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Yarnell E. Botanical medicine in pregnancy and lactation. Altern Complement Ther. 1997;3 (April):93-100.
2. Scott CR, Jacobson H. A selection of international nutritional and herbal remedies for breastfeeding concerns. Midwifery Today Int Midwife. 2005;75:38-9. PMID: 16320878
3. Amir LH, Pirotta MV, Raval M. Breastfeeding – Evidence based guidelines for the use of medicines. Aust Fam Physician. 2011;40:684-90. PMID: 21894275
4. Eglash A. Treatment of maternal hypergalactia. Breastfeed Med. 2014;9:423-5. PMID: 25361472
5. Kirsch F, Beauchamp J, Buettner A. Time-dependent aroma changes in breast milk after oral intake of a pharmacological preparation containing 1,8-cineole. Clin Nutr. 2012;31:682-92. PMID: 22405404
6. Kirsch F, Buettner A. Characterisation of the metabolites of 1,8-cineole transferred into human milk: Concentrations and ratio of enantiomers. Metabolites. 2013;3:47-71. DOI: doi:10.3390/metabo3010047
7. Kirsch F, Horst K, Rohrig W et al. Tracing metabolite profiles in human milk: studies on the odorant 1,8-cineole transferred into breast milk after oral intake. Metabolomics. 2013;9:483-96. DOI: doi:10.1007/s11306-012-0466-9

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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