The Basics
What is Talazoparib?
Used to treat HER2-negative locally advanced or metastatic breast cancer with a deleterious or suspected deleterious BRCA mutation gene.
Brand names for Talazoparib
Talzenna
How Talazoparib is classified
Antineoplastic Agents, Enzyme Inhibitors, Signal Transduction Inhibitors, PARP Inhibitors
Talazoparib During Pregnancy
Talazoparib pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Talazoparib while pregnant
N/A
Taking Talazoparib While Breastfeeding
What are recommendations for lactation if you're taking Talazoparib?
No information is available on the clinical use of talazoparib during breastfeeding. Because talazoparib is 74% bound to plasma proteins, the amount in milk is likely to be low. The manufacturer recommends that breastfeeding be discontinued during talazoparib therapy and for one month after the last dose.
Maternal / infant drug levels
No information is available on the clinical use of talazoparib during breastfeeding. Because talazoparib is 74% bound to plasma proteins, the amount in milk is likely to be low. The manufacturer recommends that breastfeeding be discontinued during talazoparib therapy and for one month after the last dose.
Possible effects of Talazoparib on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Talazoparib
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
