The Basics
What is Ticarcillin?
A panicillin almost always sold and used in combination with clavulanate as ticarcillin/clavulanic acid.
Brand names for Ticarcillin
Timentin
How Ticarcillin is classified
Anti-Infective Agents, Antibacterial Agents, Penicillins
Ticarcillin During Pregnancy
Ticarcillin pregnancy category
Category BNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Ticarcillin while pregnant
N/A
Taking Ticarcillin While Breastfeeding
What are recommendations for lactation if you're taking Ticarcillin?
Limited information indicates that ticarcillin produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant’s gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. Ticarcillin is acceptable in nursing mothers.
Maternal / infant drug levels
Limited information indicates that ticarcillin produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant’s gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. Ticarcillin is acceptable in nursing mothers.
Possible effects of Ticarcillin on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Ticarcillin
None listed
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Matsuda S, Tanno M, Kashiwakura T et al. Laboratory and clinical use of ticarcillin. Chemotherapy (Tokyo). 1977;25:2924-31.
2. Matsuda S. Transfer of antibiotics into maternal milk. Biol Res Pregnancy. 1984;5:57-60. PMID: 6743732
3. Cho N, Nakayama T, Uehara K et al. Laboratory and clinical evaluation of ticarcillin in the field of obstetrics and gynecology. Chemotherapy (Tokyo). 1977;25:2911-23.
4. von Kobyletzki D, Dalhoff A, Lindemeyer H et al. Ticarcillin serum and tissue concentrations in gynecology and obstetrics. Infection. 1983;11:144-9. PMID: 6885173
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
