The Basics
What is Tolmetin?
Used primarily to reduce hormones that cause pain, swelling, tenderness, and stiffness in conditions such as osteoarthritis and rheumatoid arthritis, including juvenile rheumatoid arthritis.
Brand names for Tolmetin
Tolectin
How Tolmetin is classified
Analgesic Agents, Nonsteroidal Antiinflammatory Agents
Tolmetin During Pregnancy
Tolmetin pregnancy category
Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Tolmetin while pregnant
Reproduction studies in rats and rabbits at doses up to 50 mg/kg (1.5 times the maximum clinical dose based on a body weight of 60 kg) revealed no evidence of teratogenesis or impaired fertility due to TOLECTIN (tolmetin sodium) . However, animal reproduction studies are not always predictive of human response. There are no adequate and well- controlled studies in pregnant women. TOLECTIN (tolmetin sodium) should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus.
Taking Tolmetin While Breastfeeding
What are recommendations for lactation if you're taking Tolmetin?
Because of the low levels of tolmetin in breastmilk and its short half-life, it is unlikely to adversely affect the breastfed infant. However, because there is no published experience with breastfeeding during tolmetin use, other agents may be preferred, especially while nursing a newborn or preterm infant.
Maternal / infant drug levels
Because of the low levels of tolmetin in breastmilk and its short half-life, it is unlikely to adversely affect the breastfed infant. However, because there is no published experience with breastfeeding during tolmetin use, other agents may be preferred, especially while nursing a newborn or preterm infant.
Possible effects of Tolmetin on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Tolmetin
Acetaminophen, Flurbiprofen, Ibuprofen, Indomethacin, Naproxen, Piroxicam.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Sagraves R, Waller ES, Goehrs HR. Tolmetin in breast milk. Drug Intell Clin Pharm. 1985;19:55-6. Letter. PMID: 3967576
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
