The Basics
What is Zileuton?
Used to prevent wheezing, shortness of breath, coughing, and chest tightness due to asthma.
Brand names for Zileuton
Zyflo
How Zileuton is classified
Anti-Asthmatic Agents, Leukotriene Antagonists, Lipoxygenase Inhibitors
Zileuton During Pregnancy
Zileuton pregnancy category
Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Zileuton while pregnant
N/A
Taking Zileuton While Breastfeeding
What are recommendations for lactation if you're taking Zileuton?
No published information is available on the use of zileuton during breastfeeding; however, manufacturer’s data indicate that the dose in milk is low. Because there is no published experience with zileuton during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Maternal / infant drug levels
No published information is available on the use of zileuton during breastfeeding; however, manufacturer’s data indicate that the dose in milk is low. Because there is no published experience with zileuton during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Possible effects of Zileuton on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Zileuton
Beclomethasone, Cromolyn, Montelukast, Terbutaline, Theophylline.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
