Dipropylene Glycol

The Basics On Dipropylene Glycol

What is Dipropylene Glycol?

A synthetic slip agent and texture enhancer.

What are other names for Dipropylene Glycol?

1,1′-DIMETHYLDIETHYLENE GLYCOL, 1,1′-OXYBIS- 2-PROPANOL, 1,1′-OXYBIS-2-PROPANOL, 1,1′-OXYDIPROPAN-2-OL, 2-PROPANOL, 1,1′-OXYBIS-, 2PROPANOL, 1,1 OXYBIS, BIS(2-HYDROXYPROPYL)ETHER, DI-1,2-PROPYLENE GLYCOL, DIPROPYLENE GLYCOL, and DIPROPYLENE GLYCOL (ISOMER UNSPECIFIED)

What is Dipropylene Glycol used for?

Dipropylene glycol finds many uses as a plasticizer, an intermediate in industrial chemical reactions, as a polymerization initiator or monomer, and as a solvent. Its low toxicity and solvent properties make it an ideal additive for perfumes and skin and hair care products.

How Dipropylene Glycol is classified

Texture Enhancer

Recommendations for using Dipropylene Glycol during pregnancy and breastfeeding

Limited data suggests no known risk

 

Dipropylene Glycol During Pregnancy

What we know about using Dipropylene Glycol while pregnant or breastfeeding

Limited information available.

The effect of the ingestion of Butylene Glycol on pregnant rats and on the metabolism of their offspring was studied. r30) Groups of pregnant rats were given water (control) or Butylene Glycol (9 percent w/v) in drinking water. Treatment was continued throughout the period of gestation and lactation. The length of gestation was not affected by the glycol. The investigators found that rats that ingested Butylene Glycol through gestation bore offspring with a slight increase in RNA content in neurones taken from the cerebral cortex at 18 days. In 8- and 18-day-old pups, protein synthesis in the liver was significantly reduced. In amino acid incorporation studies, neuronal perikarya from 8-day-old pups incorporated 45 percent more amino acids into acid-insoluble polypeptides than did controls. However, protein synthesis in neurons from 18-day-old pups was severely inhibited by maternal ingestion of the glycol. Therefore, maternal treatment with the glycol exerted opposite effects on neuronal protein synthesis at different stages of postnatal development of progeny. Amino acid incorporation by free and membrane-bound ribosomes from liver of 8- and 18-day-old pups was increased by Butylene Glycol.

General safety info about Dipropylene Glycol from CIR

Butylene Glycol, Hexylene Glycol, Ethoxydiglycol, and Dipropylene Glycol are viscous liquids used in the cosmetic industry as humectants, emulsifiers, plasticizers, and solvents. The results of acute, subchronic, and chronic oral toxicity studies using a variety of animal species indicate a low order of toxicity for the Glycols. Results of parenteral injection, inhalation, and acute and subchronic cutaneous toxicity studies likewise support a low order of toxicity. Butylene Glycol, Ethoxydiglycol, and Dipropylene Glycol caused minimal to mild irritation of rabbit skin, whereas Hexylene Clycol was moderately irritating. The Glycols produced mild to severe ocular irritation when tested in rabbits, with Hexylene Clycol producing the most severe irritation. Although undiluted Hexylene Glycol produced severe ocular irritation, a 25 percent aqueous solution produced no signs of irritation. Undiluted Butyiene Glycol was not an eye irritant to rabbits but was to humans. Human skin patch tests on undiluted Butylene Glycol and undiluted Hexylene Glycol produced a very low order of primary skin irritation. A repeated insult patch test on Butylene Glycol produced no evidence of skin sensitization. Based on the available data it is concluded the Butylene Glycol, Hexylene Glycol, Ethoxydiglycol, and Dipropylene Glycol are safe as presently used in cosmetics.

Use this, not that!

Products where you might find Dipropylene Glycol

Glycol Lactic Radiance Renewal Mask; Brazilian Bum Bum Cream; Brazilian 4 Play Moisturizing Shower Cream-Gel; Cicapair Tiger Grass Color Correcting Treatment SPF 30; Vinoperfect Brightening Glycolic Overnight Cream