The Basics On Aminobutyric Acid

What is Aminobutyric Acid?

Amino acid that has water-binding properties and may provide soothing benefits for skin.

What are other names for Aminobutyric Acid?

3-CARBOXYPROPYLAMINE, 4-AMINO- BUTANOIC ACID, 4-AMINO- BUTYRIC ACID, 4-AMINOBUTANOIC ACID, 4-AMINOBUTYRIC ACID, AMINOBUTYRIC ACID, BUTANOIC ACID, 4-AMINO-, BUTANOIC ACID, 4AMINO, BUTYRIC ACID, 4-AMINO-, PIPERIDIC ACID, and PIPERIDINIC ACID

What is Aminobutyric Acid used for?

Gabacare is an anti-aging ingredient with the following benefits: Reduce wrinkles and smooth skin. Gaba can quickly penetrate into the skin, relaxing tense muscles to reduce small wrinkles and lines.

How Aminobutyric Acid is classified

Skin-Soothing

Recommendations for using Aminobutyric Acid during pregnancy and breastfeeding

Limited data suggests no known risk

 

Aminobutyric Acid During Pregnancy

What we know about using Aminobutyric Acid while pregnant or breastfeeding

Limited information available.

Sodium PCA was not a developmental or reproductive toxicant in rats.10 Groups of 12 male and 12 female Wistar rats were dosed by gavage once daily with 0, 62.5, 250, or 1000 mg/kg bw/day sodium PCA in water. The females were dosed for 2 wks prior to mating until day 4 of lactation; the males were dosed for 14 days prior to mating and for 14 days during mating. No adverse effects on any measured parameters in the parents or offspring were observed. The no-observable adverse effect level (NOAEL) for maternal and reproductive toxicity was listed as 1000 mg/kg bw/day.

General safety info about Aminobutyric Acid from CIR

The CIR Expert Panel reassessed the safety of PCA (2-pyrrolidone-5-carboxylic acid) and its salts, and concluded that these ingredients are safe as used in cosmetic formulations; additionally these ingredients should not be used in cosmetic products in which N-nitroso compounds can be formed. The Panel reaffirmed the 1999 conclusion and added three previously un-reviewed salts of PCA to this re-review. PCA and its salts are reported to function in cosmetics as skin conditioning agents – humectants. The Panel reviewed the data from the 1999 report of PCA and sodium PCA, as well as additional data included in this report, to determine the safety of these ingredients.

Use this, not that!

Products where you might find Aminobutyric Acid

Sunday Riley GOOD GENES All-In-One Lactic Acid Treatment (1.7 oz.); Sunday Riley GOOD GENES All-In-One Lactic Acid Treatment (1 fl. oz.); Sunday Riley GOOD GENES Glycolic Acid Treatment (1.7 fl. oz.); The Ordinary Hyaluronic Acid 2% + B5; SUNDAY RILEY Good Genes All-In-One Lactic Acid Treatment; Fresh Rose & Hyaluronic Acid Deep Hydration Moisturizer

 

 

 

List of References

General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/

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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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