The Basics On Aminomethyl Propanol
What is Aminomethyl Propanol?
Aminomethyl propanol is a synthetic ingredient used in cosmetics as a pH adjuster.
What are other names for Aminomethyl Propanol?
1-PROPANOL, 2-AMINO-2-METHYL-, 1PROPANOL, 2AMINO2METHYL, 2-AMINO-2-METHYL- 1-PROPANOL, 2-AMINO-2-METHYL-1-PROPANOL, 2-AMINO-2-METHYLPROPANOL, 2-AMINOISOBUTANOL, 2-HYDROXYMETHYL-2-PROPYLAMINE, AMINOMETHYL PROPANOL, and ISOBUTANOLAMINE
What is Aminomethyl Propanol used for?
In cosmetics and personal care products, aminomethyl propanol is used in the formulation of creams and lotions, hair sprays, wave sets, hair dyes and colors, eye and facial products, and other hair and skin care products. The main function of aminomethyl propanol in these products is to establish and hold the pH.
How Aminomethyl Propanol is classified
Uncategorized, Miscellaneous
Recommendations for using Aminomethyl Propanol during pregnancy and breastfeeding
Limited data suggests no known risk
Aminomethyl Propanol During Pregnancy
What we know about using Aminomethyl Propanol while pregnant or breastfeeding
Limited information available.
The NOAEL for reproduction and teratogenicity for tromethamine using rats was ‚â• 1000 mg/kg/d. 54 Female Crl:CD(D) rats (n = 10) were orally administered tromethamine (100, 300, 1000 mg/kg/d adjusted to pH 9) by gavage. Males (n = 10) were treated for at least 2 weeks before breeding up to 29 days. Females (n = 12) were treated from 2 weeks prior to breeding, through gestation, and through 4 days of lactation for up to 54 days. Tromethamine had no effect on mating performance or conception. There were no effects to mating index, fertility index, gestation period, deliver index, and number of live pups. There were no adverse effects were observed to the F1 pups at birth.
General safety info about Aminomethyl Propanol from CIR
This is a safety assessment of tromethamine, aminomethyl propanediol, and aminoethyl propanediol in cosmetics. These ingredients function as pH adjusters. The CIR Expert Panel reviewed relevant animal and human data related to these ingredients. The similarities in molecular structures, properties, functions and uses of these ingredients enabled grouping them and using the available toxicological data to assess the safety of individual members of the group. The Panel concluded that tromethamine, aminomethyl propanediol, and aminoethyl propanediol are safe in the present practices of use and concentration described in this safety assessment in cosmetics.
Use this, not that!
Products where you might find Aminomethyl Propanol
N/A
List of References
General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/
N/A
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
