The Basics On Ascorbyl Palmitate
What is Ascorbyl Palmitate?
An ester formed from ascorbic acid and palmitic acid creating a fat-soluble form of vitamin C.
What are other names for Ascorbyl Palmitate?
6-HEXADECANOATE L-ASCORBIC ACID, 6-O-PALMITOYLASCORBIC ACID, ASCORBIC ACID PALMITATE, ASCORBIC PALMITATE, ASCORBYL 6-PALMITATE, ASCORBYL PALMITATE, ASCORBYL PALMITATE (VITAMIN C PALMITATE), ASCORBYLAPALMITIC ACID, L-ASCORBIC ACID, 6-HEXADECANOATE, LASCORBIC ACID, 6HEXADECANOATE, and PALMITOYL L-ASCORBIC ACID
What is Ascorbyl Palmitate used for?
Sodium ascorbyl phosphate (SAP) provides the same skincare benefits as Vitamin C. Upon topical application, it has been observed that SAP is converted to Vitamin C by chemicals within the skin. This includes a wide range of skincare applications, from anti-aging, pigmentation reduction, antioxidative photodamage repair, protection from free radicals and synthesis and stabilization of skin collagen and elastin. Maximal concentration for optimal percutaneous absorption was 20%.6
How Ascorbyl Palmitate is classified
Antioxidants, Vitamins
Recommendations for using Ascorbyl Palmitate during pregnancy and breastfeeding
Limited data suggests no known risk
Ascorbyl Palmitate During Pregnancy
What we know about using Ascorbyl Palmitate while pregnant or breastfeeding
Limited information available.
Computational Analyses/Predictions Ascorbyl Palmitate Using an in silico methodology (described at beginning of Toxicological Studies section), Ascorbyl Palmitate was predicted not to be a reproductive toxicant.41 Ascorbyl Stearate Using an in silico methodology (descr
General safety info about Ascorbyl Palmitate from CIR
No report found.
Use this, not that!
Products where you might find Ascorbyl Palmitate
The Ordinary Ascorbyl Glucoside Solution 12%;;1; Perricone MD Skin Clear Dietary Supplements; Lancome Bienfait Multi-Vital SPF 30 Day Cream Moisturizer
List of References
General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/
1. Nayama S, Takehana M, Kanke M, Itoh S, Ogata E, Kobayashi S. Protective effects of sodium-L-ascorbyl-2 phosphate on the development of UVB-induced damage in cultured mouse skin. Biol Pharm Bull. 1999;22(12):1301-1305. [PubMed] 2. Gönüllü U, Yener G, Uner M, Incegül T. Moisturizing potentials of ascorbyl palmitate and calcium ascorbate in various topical formulations. Int J Cosmet Sci. 2004;26(1):31-36. [PubMed] 3. Kobayashi S, Takehana M, Itoh S, Ogata E. Protective effect of magnesium-L-ascorbyl-2 phosphate against skin damage induced by UVB irradiation. Photochem Photobiol. 1996;64(1):224-228. [PubMed] 4. Wang K, Jiang H, Li W, Qiang M, Dong T, Li H. Role of Vitamin C in Skin Diseases. Front Physiol. 2018;9:819. [PubMed] 5. Smaoui S, Ben H, Adel K. Application of l-Ascorbic Acid and its Derivatives (Sodium Ascorbyl Phosphate and Magnesium Ascorbyl Phosphate) in Topical Cosmetic Formulations: Stability Studies 1. JChemSocPak. 2013;35(4):1096. 6. Pinnell S, Yang H, Omar M, et al. Topical L-ascorbic acid: percutaneous absorption studies. Dermatol Surg. 2001;27(2):137-142. [PubMed] 7. Woolery-Lloyd H, Baumann L, Ikeno H. Sodium L-ascorbyl-2-phosphate 5% lotion for the treatment of acne vulgaris: a randomized, double-blind, controlled trial. J Cosmet Dermatol. 2010;9(1):22-27. [PubMed] Related Articles: Glossary: Vitamin C Glossary: Magnesium Ascorbyl Phosphate
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
