The Basics On Brassica Campestris
What is Brassica Campestris?
Field mustard.
What are other names for Brassica Campestris?
BRASSICA CAMPESTRIS (RAPESEED) SEED OIL, BRASSICA CAMPESTRIS OIL, BRASSICA CAMPESTRIS SEED OIL, OIL OF RAPESEED, RAPE OIL, RAPESEED OIL, RAPESEED OIL; RAPESEED OIL, and RAPESEED SEED OIL
What is Brassica Campestris used for?
How Brassica Campestris is classified
Antioxidants, Emollients
Recommendations for using Brassica Campestris during pregnancy and breastfeeding
Limited data suggests no known risk
Brassica Campestris During Pregnancy
What we know about using Brassica Campestris while pregnant or breastfeeding
Limited information available.
In a two-generation feeding study, the no observed adverse effect level (NOAEL) for phytosterol esters was ≥8.1% (the highest dose tested) in the diet.59,60 Wistar rats, F0 generation, (n = 28/sex) were administered phytosterol esters (0, 1.6%, 3.2%, 8.1%) in feed for 10 weeks before mating, and continuing through gestation and weaning. The F1 generation (n = 28/sex) were fed the same diet as their F0 parents and mated after 10 weeks. The analysis of the phytosterols revealed the following breakdown: brassicasterol (2.9%), campesterol (26.7%), stigmasterol (17.7%), β-sitosterol (51.0%), cholesterol (0.2%), and unknowns (1.5%). There were no maternal or teratogenic effects attributed to the test substance. There were no effects on fertility and reproductive parameters, including sexual maturity, estrous cycle length, precoital time, and the histopathology of reproductive tissues in either generation. There were no developmental or reproductive effects observed in either generation. Necropsies were unremarkable. The NOAEL (8.1%) is equivalent to 3.3-6.5 g phytosterol esters/kg/d during the 10-week pre-mating period (~ 2.1- 4.1 g phytosterols/kg/d or 400-900 mg stigmasterol/kg/d) and 2.5-9.1 g phytosterol esters/kg/d during gestation (~1.4-5.7 g/kg/d or 300-1200 mg stigmasterol/kg/d). The authors concluded that 2.5-9.1 g phytosterol esters/kg/d and 1.54-5.62 g phytosterols/kg/d (~ 335-1219 mg stigmasterol/kg/d), dependent on the phase of the study, was the NOAEL of daily oral administration of phytosterol esters for two successive generations.59,60 There were no signs of reproductive toxicity to American minks (n = 70/sex) orally administered β-sitosterol (at 0, 5, 10 or 50 mg/kg/d) for 10 months. 61 In the second part of the study, after 7 months of exposure, males (n = 10–11) were mated with 4–5 females each. There were no differences in number of pregnant females, litter and kit numbers, postnatal mortality and development and there were no treatment-related changes. After 3 months of exposure, 15 males/group were killed and investigated for organ weights and hematological and clinical chemistry parameters. Males exhibiting low quality fur were selected for this part of the study. There were differences in body fat masses (omental, mesenteric, retroperitoneal, intra-abdominal fat) reported, but increases in fat masses were not dose dependent. There were increased blood hemoglobin and serum high-density lipoprotein cholesterol concentrations observed. Subcutaneous injections of β-sitosterol (5 mg/kg/d) for 16 to 48 days decreased sperm concentrations and fertility, and decreased testis and accessory sex tissue weights in a time-dependent manner in male Wistar rats.62 Rats administered 0.5 mg/kg/d had a decrease in sperm concentration of the caput epididymis after 48 days of treatment, but no reduction in fertility. The observed decreases in sperm concentration persisted after termination of treatment, and appeared to be due to a reduction in the rate of spermatogenesis.
General safety info about Brassica Campestris from CIR
Phytosterols function in cosmetics include skin-conditioning agents, hair conditioning agents, viscosity increasing agents, skin protectants, antioxidants, and fragrances. The Panel reviewed relevant animal and human data related to these ingredients including results of tests for estrogenic effects. The Panel concluded that phytosterols were safe as cosmetic ingredients in the practices of use and concentration of this safety assessment. Industry should use good manufacturing practices to limit impurities.
Use this, not that!
Products where you might find Brassica Campestris
Playa Supernatural Conditioner
List of References
General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/
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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.