The Basics On Cocamidopropyl Hydroxysultaine

What is Cocamidopropyl Hydroxysultaine?

Mild amphoteric surfactant derived from coconut oil.

What are other names for Cocamidopropyl Hydroxysultaine?

(3-COCAMIDOPROPYL)(2-HYDROXY-3-SULFOPROPYL)DIMETHYL HYDROXIDE, QUATERNARY AMM ONIUM COMPOUNDS, (3-COCAMIDOPROPYL)(2-HYDROXY-3-SULFOPROPYL)DIMETHYL QUATERNARY AMMONIUM COMPOUNDS HYDROXIDE, (3-COCAMIDOPROPYL)(2-HYDROXY-3-SULFOPROPYL)DIMETHYL QUATERNARY AMMONIUM COMPOUNDS, HYDROXIDE,, 1-PROPANAMINIUM, N-(3-AMINOPROPYL)-2-HYDROXY-N,N-DIMETHYL-3-SULFO, N-COCO ACYL DERIVS., HYDROXIDES,, 1-PROPANAMINIUM, N-(3-AMINOPROPYL)-2-HYDROXY-N,N-DIMETHYL-3-SULFO-, N-COCO ACYL DERIVS., INNER SALTS, 1PROPANAMINIUM, N(3AMINOPROPYL)2HYDROXYN,NDIMETHYL3SULFO, NCOCO ACYL DERIVS., HYDROXIDES, INNER SALTS, COCAMIDOPROPYL HYDROXYSULTAINE, HYDROXIDE, (3-COCAMIDOPROPYL)(2-HYDROXY-3-SULFOPROPYL)DIMETHYL QUATERNARY AMMONIUM COMPOUNDS, HYDROXIDE, QUATERNARY AMM ONIUM COMPOUNDS, (3-COCAMIDOPROPYL)(2-HYDROXY-3-SULFOPROPYL)DIMETHYL, HYDROXIDES, 1-PROPANAMINIUM, N-(3-AMINOPROPYL)-2-HYDROXY-N,N-DIMETHYL-3-SULFO, N-COCO ACYL DERIVS., INNER SALT, N,N-DIMETHYL-N-(3-COCAMIDOPROPYL)-3-AMNONIO-2-HYDROXYPROPYLSULFONATE, N-COCO ACYL DERIVS. HYDROXIDES, 1-PROPANAMINIUM, N-(3-AMINOPROPYL)-2-HYDROXY-N,N-DIMETHYL-3-SULFO, and QUATERNARY AMM ONIUM COMPOUNDS, (3-COCAMIDOPROPYL)(2-HYDROXY-3-SULFOPROPYL)DIMETHYL, HYDROXIDE,

What is Cocamidopropyl Hydroxysultaine used for?

Cocamidopropyl hydroxysultaine helps keep skin and hair soft and supple by working as a conditioning agent. It creates a creamy lather with less potential for damage to the outermost layer of skin (the stratum corneum). It can also be used as a foam booster, antistatic agent, and thickener.

How Cocamidopropyl Hydroxysultaine is classified

Cleansing Agents

Recommendations for using Cocamidopropyl Hydroxysultaine during pregnancy and breastfeeding

Limited data suggests no known risk

 

Cocamidopropyl Hydroxysultaine During Pregnancy

What we know about using Cocamidopropyl Hydroxysultaine while pregnant or breastfeeding

Limited information available.

Cocamidopropyl Hydroxysultaine The potential DART effects of 36.2% Cocamidopropyl Hydroxysultaine in aqueous solution were assessed in the short-term toxicity test described above (see TOXICOLOGICAL STUDIES – Short-Term Toxicity Studies Section above), performed in accordance with OECD test guideline 422. 5 The total litter sizes and numbers of pups of each sex were recorded. The pups were observed daily for clinical signs of toxicity. Pup body weights were recorded on days 1 and 3 post-partum. Pups, including those found dead before study termination, were submitted for a macroscopic post-mortem examination. No treatment-related effects on mating and fertility or unscheduled mortalities were observed. All animals mated within comparable mean number of days. Treatment-related body weight changes in the female rats included a dose-related decrease in mean body weight gain during the premating period and decreases in mean body weights during the pregnancy and lactation periods, which was associated with a non-statistically significant decrease in mean body weight gain during the lactation period. There were no effects on mean feed consumption in the parental animals during any period of the study. There were no relevant differences between control and treatment groups in the following parameters: mean duration of gestation, mean number of corpora lutea, mean number of implantations, mean number of pups delivered, mean pre-implantation loss and mean post-implantation loss. No treatment-related effects were observed in live births, sex-ratio, viability, or lactation indices. No treatment-related clinical signs of toxicity were observed in the pups. There were no significant effects on mean body weight gains in the pups during the post-partum period. No treatment-related findings were observed at necropsy in pups found dead during the observation period or at study end. The authors of this study of 36.2% Cocamidopropyl Hydroxysultaine concluded that the no-observed-effect-level (NOEL) for the reproductive performance of the parental animals was 300 mg/kg/day, which was also the NOEL for toxic effects on the pups.5

General safety info about Cocamidopropyl Hydroxysultaine from CIR

The Cosmetic Ingredient Review (CIR) Expert Panel assessed the safety of 13 alkyl sultaines, which are most frequently reported to function in cosmetics as antistatic agents, surfactants, and skin and hair conditioning agents. The Panel reviewed the available data to determine the safety of these ingredients. The Panel noted gaps in the available safety data for some of the alkyl sultaines in this safety assessment; the available data on some of the ingredients are sufficient, however, and can be read across to support the safety of other members of the group. The Panel concluded that these alkyl sultaines are safe in cosmetics in the present practices of use and concentration described in this safety assessment.

Use this, not that!

Products where you might find Cocamidopropyl Hydroxysultaine

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List of References

General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/

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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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