Gellidiela Acerosa Extract

The Basics On Gellidiela Acerosa Extract

What is Gellidiela Acerosa Extract?

Extract derived from a type of algae.

What are other names for Gellidiela Acerosa Extract?

EXTRACT OF GELLIDIELA ACEROSA, GELIDIELLA ACEROSA EXTRACT, GELLIDIELA ACEROSA EXTRACT, and RED MAPLEWEED EXTRACT

What is Gellidiela Acerosa Extract used for?

How Gellidiela Acerosa Extract is classified

Antioxidants, Emollients, Plant Extracts

Recommendations for using Gellidiela Acerosa Extract during pregnancy and breastfeeding

Limited data suggests no known risk

 

Gellidiela Acerosa Extract During Pregnancy

What we know about using Gellidiela Acerosa Extract while pregnant or breastfeeding

Limited information available.

The potential reproductive toxicity of a crude extract of Gelidiella acerosa was evaluated in albino rats.41 In order to prepare the crude extract, Gelidiella acerosa was collected and extracted into a 1:1 methanol:methylene chloride solvent system and co-precipitated with polyvinylpyrrolidone (PVP). The co-precipitate was dissolved in distilled water to obtain the 1000 mg/kg dose in 1 mL aliquots. Pregnant rats (5/group) were orally administered (via gavage) either 1 mL vehicle (PVP in distilled water) or 1 mL of the crude extract (PVP co-precipitate) in distilled water, daily, at different stages of gestation (on day 1 only, days 1 – 3, days 4 – 6, or days 7 – 8). On day 14 of gestation, animals were laparotomized, and the number of implantation sites, resorption sites, number of viable embryos, and the gross appearance and number of corpora lutea were observed. Administration of the crude extract did not cause significant (p > 0.05) change in any of the parameters evaluated in the animals treated during day 1, days 1 – 3, or days 4 – 6 of gestation. Administration of the crude extract on day 7 – 8 of gestation significantly (p < 0.01) reduced the total number of viable implantation sites (by 72%), and significantly (p < 0.01) increased the number of resorption sites and post-implantation loss (by 89%). Within the same study, 12 rats were divided into two equal groups, and one received 1 mL of the vehicle/day, and the other 1 mL of the crude extract/day. Administration occurred on days 1 - 7 of gestation. After examination of the number of implantation sites, resorption sites, and viable embryos, animals were sutured, treated locally and subcutaneously with antibiotics, and allowed to recover. Apparent size and distribution of the embryos in the uterine horns were also noted. These animals were re-laparotomized on day 14 of gestation, and the above parameters were recorded. The size, appearance, and color of the implants in treated animals were similar to those of the control; however, a clumping of embryos towards the cervical end of the uterine horns was evident in crude extract-treated rats. Animals were also observed on day 14 of gestation. Control animals had the same number of viable implants on day 14 as on day 8 of pregnancy. All embryos in the treated group on day 14 of gestation were non-viable and resorbing. There was a 100% post-implantation loss in the treated group (p < 0.001).

General safety info about Gellidiela Acerosa Extract from CIR

No report found.

Use this, not that!

Products where you might find Gellidiela Acerosa Extract

GROWN ALCHEMIST Intensive Hand Cream – Persian Rose & Argan Extract (2.29 oz.); skyn ICELAND Icelandic Relief Eye Cream with Glacial Flower Extract (0.49 oz.);skyn ICELAND Oxygen Infusion Night Cream with Glacial Flower Extract (1.98 oz.); Supergoop! PLAY Everyday Lotion SPF 50 with Sunflower Extract; Kiehl’s Since 1851 Calendula Herbal Extract Alcohol Free Toner; AMOREPACIFIC Vintage Single Extract Essence