The Basics On Glycereth-26
What is Glycereth-26?
Used as an emollient and thickening agent in cosmetics.
What are other names for Glycereth-26?
ETHOXYLATED GLYCERIN; ETHOXYLATED GLYCERINE; GLYCERINE ETHOXYLATE; GLYCERINE, ETHOXYLATED; GLYCERIN, ETHYLENE OXIDE CONDENSATE; GLYCEROL, ETHOXYLATED; GLYCEROL, ETHOXYLATED; GLYCEROL POLY(OXYETHYLENE), GLYCERETH-26, PEG-26 GLYCERYL ETHER, POLY(OXY-1,2-ETHANEDIYL), .ALPHA.,.ALPHA.’,.ALPHA.”-1,2,3-PROPANETRIYLTRIS[.OMEGA.-HYDROXY-, POLYETHYLENE GLYCOL (26) GLYCERYL ETHER, POLYOXYETHYLENE (26) GLYCERYL ETHER, and POLYOXYETHYLENE GLYCERYL ETHER
What is Glycereth-26 used for?
How Glycereth-26 is classified
Thickeners/Emulsifiers, Emollients
Recommendations for using Glycereth-26 during pregnancy and breastfeeding
Limited data suggests no known risk
Glycereth-26 During Pregnancy
What we know about using Glycereth-26 while pregnant or breastfeeding
Limited information available.
Oral Propoxylated nitrilotriethanol (a read-across source for ethoxylated glycerol, according to the ECHA dossier) A reproductive/developmental toxicity screen test was performed in accord with OECD TG 421.4 Groups of 12 male and 12 female Wistar rats were administered a propoxylated nitrilotriethanol (average MW 280 g/mol) in water at doses of 0, 100, 300, and 1000 mg/kg bw by gavage. Concentration of test article and days of dosing were not specified. Typically, in a study following this TG females are dosed throughout the study; however, that was not stated in the summary. The rats in each dose group were allowed to deliver. Body weights were determined daily during pregnancy, and dams were examined shortly after birth and on day 4 postpartum. Transient salivation was noted in both sexes of the parental rats dosed with 1000 mg/kg. Slight body weight loss occurred in females of the 1000 mg/kg dose group during lactation, and marginal body weight gains were noted during the premating period at all doses. No significant embryotoxic or teratogenic effects nor abnormalities were noted, and no effects on reproductive performance were observed. Four pups from the F1 generations developed filiformed tip at 1000 mg/kg compared to 3 pups in the control group. No adverse effect levels (NOELs) were determined to be 100 mg/kg in females and 300 mg/kg in males, based increased incidence of salivation. Under the test conditions the NOAEL was derived as 1000 mg/kg because the mild body weight loss observed with females at the highest dose group (1000 mg/kg bw/day) was considered to be a non-adverse treatment-related effect, as it follows a statistically significant increased body weight gain compared to the control group in the premating phase.
General safety info about Glycereth-26 from CIR
No report found.
Use this, not that!
Products where you might find Glycereth-26
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List of References
General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/
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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.