The Basics On Glycereth-26 Phosphate

What is Glycereth-26 Phosphate?

Used as an emollient and thickening agent in cosmetics.

What are other names for Glycereth-26 Phosphate?

ETHOXYLATED GLYCERIN; ETHOXYLATED GLYCERINE; GLYCERINE ETHOXYLATE; GLYCERINE, ETHOXYLATED; GLYCERIN, ETHYLENE OXIDE CONDENSATE; GLYCEROL, ETHOXYLATED; GLYCEROL, ETHOXYLATED; GLYCEROL POLY(OXYETHYLENE), GLYCERETH-26, PEG-26 GLYCERYL ETHER, POLY(OXY-1,2-ETHANEDIYL), .ALPHA.,.ALPHA.’,.ALPHA.”-1,2,3-PROPANETRIYLTRIS[.OMEGA.-HYDROXY-, POLYETHYLENE GLYCOL (26) GLYCERYL ETHER, POLYOXYETHYLENE (26) GLYCERYL ETHER, and POLYOXYETHYLENE GLYCERYL ETHER

What is Glycereth-26 Phosphate used for?

Categories: Thickeners/Emulsifiers, Emollients Used as an emollient and thickening agent in cosmetics.

How Glycereth-26 Phosphate is classified

Thickeners/Emulsifiers, Emollients

Recommendations for using Glycereth-26 Phosphate during pregnancy and breastfeeding

Limited data suggests no known risk

 

Glycereth-26 Phosphate During Pregnancy

What we know about using Glycereth-26 Phosphate while pregnant or breastfeeding

Limited information available.

Oral Propoxylated nitrilotriethanol (a read-across source for “ethoxylated glycerol,” according to the ECHA dossier) A reproductive/developmental toxicity screen test was performed in accord with OECD TG 421.4 Groups of 12 male and 12 female Wistar rats were administered a propoxylated nitrilotriethanol (average MW 280 g/mol) in water at doses of 0, 100, 300, and 1000 mg/kg bw, by gavage. Concentration of test article and days of dosing were not specified. Typically, in a study following this TG females are dosed throughout the study; however, that was not stated in the summary. The rats in each dose group were allowed to deliver. Body weights were determined daily during pregnancy, and dams were examined shortly after birth and on day 4 postpartum. Transient salivation was noted in both sexes of the parental rats dosed with 1000 mg/kg. Slight body weight loss occurred in females of the 1000 mg/kg dose group during lactation, and marginal body weight gains were noted during the premating period at all doses. Neither significant embryotoxic or teratogenic effects, nor abnormalities, were noted, and no effects on reproductive performance were observed. Four pups from the F1 generation developed filiformed tip at 1000 mg/kg, compared to 3 pups in the control group. No adverse effect levels (NOELs) were determined to be 100 mg/kg in females and 300 mg/kg in males, based on increased incidence of salivation. Under the test conditions, the NOAEL was derived as 1000 mg/kg because reduction of body weight was observed with females at the highest dose group (1000 mg/kg bw/day). The mild weight loss was considered to be a non-adverse treatment-related effect, as it follows a statistically significant increased body weight gain compared to the control group in the premating phase.

General safety info about Glycereth-26 Phosphate from CIR

No report found.

Use this, not that!

Products where you might find Glycereth-26 Phosphate

Moroccanoil Moisture Repair Conditioner; BeautyBio GloPRO Microneedling Starter Set 8-Piece AM+PM Routine; Moroccanoil Extra Volume Shampoo

 

 

 

List of References

General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/

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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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