The Basics On Glyceryl Distearate
What is Glyceryl Distearate?
Used as an emollient and thickening agent in cosmetics.
What are other names for Glyceryl Distearate?
DIESTER WITH 1,2,3-PROPANETRIOL OCTADECANOIC ACID, DISTEARIC ACID, DIESTER WITH GLYCEROL, DISTEARIN, DISTEAROYLGLYCEROL, GLYCERIN DISTEARATE, GLYCEROL DISTEARATE, GLYCERYL DISTEARATE, OCTADECANOIC ACID, DIESTER WITH 1,2,3-PROPANETRIOL, OCTADECANOIC ACID, DIESTER WITH 1,2,3PROPANETRIOL, and STEARIC ACID DIGLYCERIDE
What is Glyceryl Distearate used for?
How Glyceryl Distearate is classified
Thickeners/Emulsifiers, Emollients
Recommendations for using Glyceryl Distearate during pregnancy and breastfeeding
Limited data suggests no known risk
Glyceryl Distearate During Pregnancy
What we know about using Glyceryl Distearate while pregnant or breastfeeding
Limited information available.
A reproduction/developmental toxicity screening test was conducted in male and female Sprague-Dawley rats for glyceryl oleate.21 Both males and females were dosed by gavage with 0, 100, 300, or 1000 mg/kg bw/day glyceryl oleate in corn oil once daily for 14 days prior to mating; the males were dosed for an additional 28 days, and dosing of the females continued until day 4 of lactation. The groups were comprised of 12 females for the control and 3 test groups, 7 males in the control and high dose groups, and 12 males in the low- and mid-dose groups. A satellite group of 5 males and 5 females were dosed for 42 days, with a 14-day post-dosing observation period. The NOAELs for systemic toxicity (males and females), fertility (males and females), and development (F1 generation) were 1000 mg/kg bw/day. No effects related to the administration of the test-article were observed in parental animals or offspring. For Read-Across In the 28-day oral toxicity study with 0, 100, 300 and 1000 mg/kg/day glycerides, C8-18 and C18-unsatd. mono- and di-, acetates in polyethylene glycol described in Table 9 (Repeated Dose Toxicity Studies), an additional 10 female Wistar Han rats were included in each group to assess reproduction and developmental toxicity. 20 After a minimum of 14 days of dosing, females of the reproduction study group were cohabitated with a male from the same treatment group. The test females were dosed for a total of 41-49 days, i.e. during those 2 weeks prior to mating, during mating, during post-coitum, and during at least 4 days of lactation. No treatment-related effects were observed, and the NOAEL for parental fertility was 1000 mg/kg bw/day. Glyceryl Hydrogenated Rosinate and Glyceryl Rosinate Following the administration of hexane extracts of Pinus ponderosa needles to mice by stomach tube, increased embryonic resorptions were observed.25 Glyceryl rosinate and glyceryl hydrogenated rosinate are esters of glycerin and acids derived from rosin, and rosin is obtained from trees of various species of Pinus.
General safety info about Glyceryl Distearate from CIR
No report found.
Use this, not that!
Products where you might find Glyceryl Distearate
Farmacy Very Cherry Bright 15% Clean Vitamin C Serum with Acerola Cherry, Beautycounter Counter+ All Bright C Serum, Anastasia Beverly Hills Lash Brag Volumizing Mascara
List of References
General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/
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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.