The Basics On Hydroxyethyl Urea

What is Hydroxyethyl Urea?

A synthetic derivative of urea.

What are other names for Hydroxyethyl Urea?

HYDROXYETHYL UREA and UREA, (HYDROXYETHYL)-

What is Hydroxyethyl Urea used for?

A synthetic ingredient that serves to hydrate skin and help maintain a normal moisture balance in skin’s uppermost layers.

How Hydroxyethyl Urea is classified

Hydration, Skin-Replenishing

Recommendations for using Hydroxyethyl Urea during pregnancy and breastfeeding

Avoid

 

Hydroxyethyl Urea During Pregnancy

What we know about using Hydroxyethyl Urea while pregnant or breastfeeding

When used in lower concentrations (10 percent), it is an excellent humectant and keratolytic agent. When used in higher concentrations (20 to 30 percent), it is a preservative that can cause irritation and inflammation.In addition to its risk of irritation, urea has come under attack because it is a formaldehyde-releasing ingredient. However, the amount of formaldehyde released by urea in skin care products is negligible, which is why the FDA and CIR continue to deem it safe for use in cosmetics.

The developmental and reproductive toxicity of an aq. solution containing 57.58% Hydroxyethyl Urea was dermally-applied using 4 groups of 25 female Sprague-Dawley rats.2,3 Open applications of 0, 100, 330, and 1000 mg/kg bw/day of the test substance in deionized water were applied 6 hours a day on days 6 through 19 of gestation. Elizabethan collars were placed around the neck of each animal during the exposure period. None of the animals died during the study. Mean feed consumption for females in the 1000 mg/kg bw/day group was statistically significantly lower than that of controls during the treatment period. However, there were no statistically significant differences in mean body weights or body weight gain between the control and test groups. No reproductive or developmental effects were observed. The NOAEL was established as 1000 mg/kg bw/day for both maternal and developmental toxicity.

General safety info about Hydroxyethyl Urea from CIR

No report found.

Use this, not that!

Coming soon!

Products where you might find Hydroxyethyl Urea

Guinot Creme Hydra Beaute (1.7 oz.); Bioelements Moisture x10 (1 fl. oz.); SkinCeuticals Body Retexturing Treatment (6.7 fl. oz.); Tatcha The Water Cream; Tatcha The Deep Cleanse Exfoliating Cleanser; Tatcha The Rice Polish Foaming Enzyme Powder

 

 

 

List of References

General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/

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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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