The Basics On Ivy Extract

What is Ivy Extract?

Plant extract that can be a skin sensitizer due to its stimulant and astringent properties.

What are other names for Ivy Extract?

EXTRACT OF HEDERA HELIX, EXTRACT OF IVY, HEDERA HELIX (IVY) EXTRACT, HEDERA HELIX EXTRACT, IVY EXTRACT, and IVY, HEDERA HELIX, EXT.

What is Ivy Extract used for?

On a surface level, ivy leaf extract has been praised for thoroughly hydrating the skin and relieving irritation from psoriasis, eczema, acne, and other skin-related conditions.

How Ivy Extract is classified

Plant Extracts, Sensitizing

Recommendations for using Ivy Extract during pregnancy and breastfeeding

Avoid

 

Ivy Extract During Pregnancy

What we know about using Ivy Extract while pregnant or breastfeeding

Limited information available.

Oral Eucalyptus Globulus Leaf Oil In a combined repeated dose and reproduction/developmental study, Eucalyptus Globulus Leaf Oil (100, 300, or 1000 mg/kg/day; in corn oil) was administered by gavage to Crl:CD(SD) rats (n = 10/sex).10 The study was conducted in accordance with Organisation of Economic Co-operation and Development Guidelines (OECD GL) 422. Males were treated starting from 2 weeks before mating for at least 5 weeks; females were treated from 2 weeks before mating until lactation day 6. The adults and offspring rats were then killed and necropsied. [For results related to short-term toxicity, see Short-Term Toxicity Studies] There were no adverse effects detected in reproductive assessments on estrous cycles, mating performance and fertility, gestation length and parturition observations, and reproductive performance. There were no significant effects of the Eucalyptus Globulus Leaf Oil on litter size, offspring survival indices or sex ratio. The body weights of offspring of the treatment groups at birth were similar to that of the control group. However, body weight gains of male and female offspring in the 1000 mg/kg/day group were low (approximately 27% to 28% lower than the control group), and by day 4 after parturition, absolute body weights of this group were also significantly lower than that of the control group. A slightly increased incidence of “cold to touch” was observed in litters in the 1000 mg/kg/day group. At microscopic examination, there were no findings attributed to treatment for offspring that died and were examined during the experiment or were killed and examined at the end of the experiment. Under the test condition, the NOAEL for the females was considered to be 300 mg/kg/day for systemic toxicity, based on lower body weight gain and feed consumption during gestation. The authors stated that both findings appeared to be associated with pregnancy status. It was not possible to link this effect to the taste of the substance since females had shown a significant duration of normal body weight and feed performance prior to Day 6 of gestation and after birth of the pups. These latter observations appeared to indicate recovery in females. The NOAEL for developmental toxicity was 300 mg/kg/day, which was based on lower offspring body weight gain, and clinical signs (pups cold to touch) that were only observed in the 1000 mg/kg/day group. This effect may be associated with test material entering the milk. The authors note that fat soluble test materials have a higher chance of becoming incorporated in the milk and Eucalyptus Globulus Leaf Oil is fat soluble. A NOAEL at 300 mg/kg/day was determined for systemic effects in the offspring based on the magnitude of the weight reduction, which was quite high. The effects on offspring body weight were not selective and have been observed at a dose producing maternal toxicity, and therefore the substance was not considered to be a selective reproductive toxicant. The NOAEL for reproductive toxicity was 1000 mg/kg/day, since no adverse effects were observed for any reproductive parameters.

General safety info about Ivy Extract from CIR

The reported functions of the Eucalyptus globulus (eucalyptus)-derived ingredients include abrasive, fragrance ingredient, and skinconditioning agent (miscellaneous and occlusive). The Cosmetic Ingredient Review (CIR) Expert Panel reviewed the relevant data on these ingredients. Because final product formulations may contain multiple botanicals, each containing similar constituents of concern, formulators are advised to be aware of these constituents and to avoid reaching levels that may be hazardous to consumers. Industry should use good manufacturing practices to limit impurities. The Panel concluded that Eucalyptus globulus (eucalyptus)-derived ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-sensitizing.

Use this, not that!

Coming soon!

Products where you might find Ivy Extract

DERMAFLASH DERMAPORE Ultrasonic Pore Extractor & Serum Infuser; DERMAFLASH DERMAPORE Ultrasonic Pore Extractor & Serum Infuser – Icy Green (5 piece); N/A

 

 

 

List of References

General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/

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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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