Magnesium Pca

The Basics On Magnesium Pca

What is Magnesium Pca?

Magnesium PCA is the magnesium salt of PCA (pyrrolidone carboxylic acid), which is part of skin’s intercellular matrix.

What are other names for Magnesium Pca?

MAGNESIUM PCA

What is Magnesium Pca used for?

Magnesium PCA therefore plays an influential role in what’s known as skin’s natural moisturizing factor. As an electrolyte mineral, magnesium plays a role in enhancing skin hydration and barrier repair.

How Magnesium Pca is classified

Hydration, Skin-Replenishing

Recommendations for using Magnesium Pca during pregnancy and breastfeeding

Limited data suggests no known risk

 

Magnesium Pca During Pregnancy

What we know about using Magnesium Pca while pregnant or breastfeeding

Limited information available.

PCA was not a developmental or reproductive toxicant in rats.3 Groups of 12 male and 12 female Wistar rats were dosed by gavage once daily with O, 62.5, 250, or 1000 mg/kg body weight/day sodium PCA in water. The females were dosed for 2 weeks prior to mating until day 4 of lactation; the males were dosed for 14 days prior to mating and for 14 days during mating. No adverse effects on any measured parameters in the parents or offspring were observed. The no observable adverse effect level (NOAEL) for maternal and reproductive toxicity was listed as 1000 mg/kg body weight/day. Ocular Irritation No ocular irritation was observed when 50% aqueous sodium PCA were instilled into the conjunctival sac of the eye of rabbits. The ocular ilTitation potential ofsodium PCA was evaluated in vitro using a chicken eye test method for identifying ocular corrosives and severe irritants; sodium PCA was classified as nonirritating? Sodium PCA also was found to be nonirritating to rabbit eyes in an in vivo study. Sodium PCA, 0.1 g neat, was instilled into the conjunctival sac ofone eye of3 New Zealand white rabbits, and the eyes were rinsed after I hour. Slight conjunctival redness and discharge were observed in all 3 animals I hour after administration; all reactions were reversed within 48 hours, and sodium PCA was considered nonirritating.

General safety info about Magnesium Pca from CIR

The Cosmetic Ingredient Review Expert panel reassessed the saf” of 2-pyrrolidone-5-carboxylic acid (PCA) and sodium PCA; the Panel added 3 previously unreviewed salts (calcium, magnesium, and potassium) of PCA to this safety assessment. 2-Pyrrolidone-5-carboxylic acid and its salts are reported to function in cosmetics as skin conditioning agents‚Äîhumectants. The Panel reviewed the data fran the 1999 report of PCA and sodium PCA as well as additional data included in fis report. to determine the safety of these ingredients. The panel concluded that PCA and its salts are safe in cosmetics in the present practices of use and concentration; additionally. these ingredients should not used in cosrnetic products in which N-nitroso cornpounds

Use this, not that!

Products where you might find Magnesium Pca

The Nue Co. Magnesium Ease (30 ml.); REN Clean Skincare Atlantic Kelp and Magnesium Body Wash (10.2 fl. oz.); REN Clean Skincare Atlantic Kelp And Magnesium Salt Anti-Fatigue Exfoliating Body Scrub (11.2 fl. oz.); Drunk Elephant F-Balm Electrolyte Waterfacial Mask