The Basics On Melia Azadirachta (Chinaberry) Leaf Extract
What is Melia Azadirachta (Chinaberry) Leaf Extract?
Extract from the leaf of the neem plant.
What are other names for Melia Azadirachta (Chinaberry) Leaf Extract?
AZADIRACHTA INDICA (NEEM) EXTRACT, EXTRACT OF MELIA AZADIRACHTA, EXTRACT OF NEEM, MELIA AZADIRACHTA (NEEM) EXTRACT, MELIA AZADIRACHTA EXTRACT, NEEM (MELIA AZADIRACHTA) EXTRACT, and NEEM EXTRACT
What is Melia Azadirachta (Chinaberry) Leaf Extract used for?
How Melia Azadirachta (Chinaberry) Leaf Extract is classified
Plant Extracts, Antioxidants
Recommendations for using Melia Azadirachta (Chinaberry) Leaf Extract during pregnancy and breastfeeding
Limited data suggests no known risk
Melia Azadirachta (Chinaberry) Leaf Extract During Pregnancy
What we know about using Melia Azadirachta (Chinaberry) Leaf Extract while pregnant or breastfeeding
Limited information available.
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General safety info about Melia Azadirachta (Chinaberry) Leaf Extract from CIR
Triatoma infestans is the principal vector of Trypanosoma cruzi, parasite responsible of Chagas’s Disease transmission in Argentina. Pyrethroids have become common pesticides for the control of T. infestans but increasing resistance encourages the search of new alternatives and the use of natural products for biological control arises as a new strategy. Melia azedarach L. is originated from the Himalaya’s region and several compounds are part of its rich phytochemistry. Folk medicine of the plant is due to its repellent and insecticidal activities. Aims of this work were to evaluate the repellent activity of methanolic and acetonic extracts from fruits of M. azedarach by means of the area preference method of fifth and first nymph stages as well as to test the acute lethal effect of the more repellent extract by means of direct application on cuticle on both stages. For repellence, qualitative filter papers were divided into two halves, one treated with methanolic (ME) or acetonic (AC) extract and the other without treatment. Controls were impregnated half with methanol or acetone and half without the solvents. One nymph was located in each Petri or well and repellence percentage was determined. For the lethal effect, fasted and fed to repletion 5th stage nymphs were topically administered with different concentrations of AC and deaths were registered after 24, 48, 72, 96, and 120 h. Phytochemical analysis of extracts was performed as well. AC demonstrated high repellent activity (100%, both stages), whereas ME extract activity was slight (10‚Äì21%). AC extract was selected for lethal assays due to early repellent activity. Fed to repletion nymphs were more sensitive to the lethal activity of the extract when compared to fasted nymphs (LD50: 11.5 vs. 23.1 Œºg/insect, respectively). Phytochemistry assays of extracts showed a higher concentration of flavonoids, alkaloids and triterpenes for AC. Considering these results, next assays will include the test of Melia azedarach extract on T. infestans that are resistant to pyrethroids for a possible synergism between AC and the pesticides.
Use this, not that!
Products where you might find Melia Azadirachta (Chinaberry) Leaf Extract
Supergoop! PLAY Everyday Lotion SPF 50 with Sunflower Extract; Kiehl’s Since 1851 Calendula Herbal Extract Alcohol Free Toner; AMOREPACIFIC Vintage Single Extract Essence
List of References
General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/
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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
