The Basics On Methyl Gluceth-20

What is Methyl Gluceth-20?

Liquid that functions as a water-binding and skin-conditioning agent.

What are other names for Methyl Gluceth-20?

METHYL GLUCETH-20

What is Methyl Gluceth-20 used for?

How Methyl Gluceth-20 is classified

Skin-Softening

Recommendations for using Methyl Gluceth-20 during pregnancy and breastfeeding

Limited data suggests no known risk

 

Methyl Gluceth-20 During Pregnancy

What we know about using Methyl Gluceth-20 while pregnant or breastfeeding

Limited information available.

A combined repeated dose toxicity study with a reproduction/ developmental toxicity screening test was performed according to the OECD 422 test protocol. 7 Isostearic acid, esters with methyl a-D-glucoside (in 1% aqueous carboxymethyl cellulose) was administered orally (gavage) to 10 male and 10 female Han rats/dose group at 50, 150, and 1,000 mg/kg body weight per day. The fourth group served as the negative control. The males were dosed for 2 weeks prior to mating, during mating, and up to termination (30 days total). Females were dosed for 2 weeks prior to mating, during mating, during post coitum, and for at least 4 days of lactation (42-44 days total). Ten litters per dose group were delivered. There were also no treatment-related changes in reproduction, breeding, or pup development. The reproduction, breeding, and developmental NOAEL was defined as 21,000 mg/kg/d. Results relating to repeated dose toxicity in adult rats are included in that section of the report.

General safety info about Methyl Gluceth-20 from CIR

The Cosmetic Ingredient Review Expert Panel reviewed the safety of methyl glucose polyethers and esters which function in cosmetics as skin/hair-conditioning agents, surfactants, or viscosity increasing agents. The esters included in this assessment are mono-, di-, or tricarboxyester substituted methyl glucosides, and the polyethers are mixtures of various chain lengths. The Panel reviewed available animal and clinical data, including the molecular weights, log Kows, and other properties in making its determination of safety on these ingredients. Where there were data gaps, similarities between molecular structures, physicochemical and biological characteristics, and functions and concentrations in cosmetics allowed for extrapolation of the available toxicological data to assess the safety of the entire group. The Panel concluded that there likely would be no significant systemic exposure from cosmetic use of these ingredients, and that these ingredients are safe in cosmetic formulations in the present

Use this, not that!

Products where you might find Methyl Gluceth-20

Maison Louis Marie Le Bouquet Candle Trio Set; Maison Louis Marie Antidris Cassis Candle; Maison Louis Marie No. 09 Vallee de Farney Candle

 

 

 

List of References

General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/

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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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