Peg-10 Dimethicone

The Basics On Peg-10 Dimethicone

What is Peg-10 Dimethicone?

What are other names for Peg-10 Dimethicone?

PEG-10 DIMETHICONE

What is Peg-10 Dimethicone used for?

Peg-10 dimethicone is a type of silicone that is used in hair and skin care products as a conditioning agent, lubricant, and skin protectant

How Peg-10 Dimethicone is classified

Silicones, Emollients, Cleansing Agents

Recommendations for using Peg-10 Dimethicone during pregnancy and breastfeeding

Limited data suggests no known risk

 

Peg-10 Dimethicone During Pregnancy

What we know about using Peg-10 Dimethicone while pregnant or breastfeeding

Limited information available.

PEG-12 DIMETHICONE Dermally administered PEG-12 dimethicone (100%; 0, 50, 100 or 200 mg/kg) was not embryotoxic or teratogenic in New Zealand White rabbits on days 6 through 18 of gestation.28 PEG-12 dimethicone or water (control) was administered to the skin of pregnant New Zealand white rabbits on days 6 through 18 of gestation. Litters were collected by cesarean section on day 29 and the fetuses examined for external, visceral or skeletal defects. No adverse effects were observed in mean maternal body weight, feed consumption or liver weights of the treated rabbits. No differences were observed in the number of implantation sites, number of live fetuses per litter, mean litter size, fetal body weight or crown-rump length between the control and treated groups. The incidence of resorption among the total fetal population of rabbits treated with test material was similar to that of the control group. No single alteration was observed in any of the treated litters which was different from the control group. No treatment related signs of toxicity or behavioral changes were observed in any of the pregnant rabbits. Three rabbits in the 50-mg/kg/d group, 1 in the 100-mg/kg/d group, and 3 in the 200-mg/kg/d group died during the study. Some pregnancies were terminated because of Pasteurella multocida infection, a known abortifacient in rabbits. GENERIC SILOXANES AND SILICONES, DI-METHYL, 3-HYDROXYPROPYL METHYL ETHOXYLATED New Zealand albino rabbit does (n=30) exhibited increased numbers of resorption sites when siloxanes and silicones, 3-hydroxypropyl methyl, di-methyl ethoxylated (generic compounds that fall within the description of the ingredients in this safety assessment; CAS No. 68937-54-2; 200 mg/kg in corn oil) were dermally administered to shaved backs of the does (~10% body surface) on gestation days 6 to 18.32 There were no deaths attributed to the test material. One pup in the treatment group displayed clubbing of the extremities, partial acranius, and an umbilical hernia. The 24-hour survival of fetuses, abnormalities in the fetuses, and number of abnormal fetuses were similar across both control groups. No dermal effects were reported for the dams. Subsequent testing of the test substance demonstrated that it was neither embryotoxic nor teratogenic when dermally administered to New Zealand white rabbits at doses of 50, 100, or 200 mg/kg (data not provided). The two control groups were administered the vehicle or nothing. Does were killed and necropsied on gestation day 29.

General safety info about Peg-10 Dimethicone from CIR

No report found.

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Products where you might find Peg-10 Dimethicone

N/A