Pentaerythrityl Tetraisostearate

The Basics On Pentaerythrityl Tetraisostearate

What is Pentaerythrityl Tetraisostearate?

A non-aqueous ester that functions as a thickener and binding agent.

What are other names for Pentaerythrityl Tetraisostearate?

2,2-HYDROXYMETHYL-1,3-PROPANEDIOL TETRAISOSTEARATE; PENTAERYTHRITOL TETRAISOSTEARATE, 2,2-BIS[[(1-ISOOCTADECYL)OXY]METHYL]-1,3-PROPANEDIYL ISOOCTADECANOATE, 2,2-BIS[[(1-OXOISOOCTADECYL)OXY]METHYL]-1,3-PROPANEDIYL BIS(ISOOCTADECANOATE), 2,2-BIS[[(1-OXOISOOCTADECYL)OXY]METHYL]-1,3-PROPANEDIYL ESTER ISOOCTADECANOIC ACID, ISOOCTADECANOIC ACID, 2,2-BIS[[(1-OXOISOOCTADECYL)OXY]METHYL]-1,3-PROPANEDIYL ESTER, PENTAERYTHRITOL TETRAISOOCTANOATE, PENTAERYTHRITOL TETRAISOSTEARATE, and PENTAERYTHRITYL TETRAISOSTEARATE

What is Pentaerythrityl Tetraisostearate used for?

How Pentaerythrityl Tetraisostearate is classified

Texture Enhancer

Recommendations for using Pentaerythrityl Tetraisostearate during pregnancy and breastfeeding

Limited data suggests no known risk

 

Pentaerythrityl Tetraisostearate During Pregnancy

What we know about using Pentaerythrityl Tetraisostearate while pregnant or breastfeeding

Limited information available.

Pentaerythrityl tetra C5-9 acid esters (0, 800, 2000 mg/kg) were dermally administered to clipped backs of Sprague-Dawley rats (n = 10/sex) for 5 days/week for 13 weeks.26 There were no effects noted in sperm morphology. Gross necropsy and histopathology of the ovaries, testis, epididymides, uteruses, and vaginas were unremarkable. Pentaerythrityl tetra C5-9 acid esters (0, 800 or 2000 mg/kg/d) were applied to the clipped backs of Sprague-Dawley rats (n = 20) on days 0 – 19 of gestation.30 Neither maternal parameters (food consumption, body weight gains) monitored throughout gestation (days 0-19) nor reproductive parameters (number of implants, resorptions, or viable fetuses) were adversely affected by the test substance. No evidence of teratogenicity was observed by external examination of fetuses. Mean fetal body weights and crown-rump distances were similar in all groups.

General safety info about Pentaerythrityl Tetraisostearate from CIR

The Cosmetic Ingredient Review Expert Panel reviewed the safety of 16 pentaerythrityl tetraester compounds used in cosmetics, including the widely used pentaerythrityl tetraisostearate. The functions of these ingredients include: hair conditioning agents; skin-conditioning agents – miscellaneous; binders; skin-conditioning agents Рocclusive; viscosity increasing agents Рnonaqueous; and skin-conditioning agents – emollient. The Panel reviewed available animal and human data related to these ingredients along with previous safety assessments of the fatty acid moieties. The Panel concluded that pentaerythrityl tetraisostearate and the other pentaerythrityl tetraester compounds were safe as cosmetic ingredients in the practices of use and concentration as given in this safety assessment.

Use this, not that!

Products where you might find Pentaerythrityl Tetraisostearate

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