The Basics On Polyquaterniums
What is Polyquaterniums?
Group of ingredients used primarily in hair-care products for their antistatic and film-forming properties.
What are other names for Polyquaterniums?
2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL ETHER, CHLORIDE, 2-HYDROXYETHYL 2-(2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPOXY)ETHYL CELLULOSE, 2-HYDROXYETHYL 2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL ETHER CHLORIDE CELLULOSE, 2-HYDROXYETHYL 23-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL ETHER CHLORIDE CELLULOSE, 2-[2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPOXY]ETHYL ETHER CHLORIDE CELLULOSE, 2-[2-HYDROXY-3-TRIMETHYLAMMONO)PROPOXY] ETHYL ETHER CHLORIDE CELLULOSE, CELLULOSE, 2-HYDROXYETHYL 2-(2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPOXY)ETHYL, CELLULOSE, 2-HYDROXYETHYL 2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL ETHER, CHLORIDE, CELLULOSE, 2-HYDROXYETHYL 23-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL ETHER, CHLORIDE, CELLULOSE, 2-[2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPOXY]ETHYL ETHER, CHLORIDE, CELLULOSE, 2-[2-HYDROXY-3-TRIMETHYLAMMONO)PROPOXY] ETHYL ETHER, CHLORIDE, CELLULOSE, ETHER WITH .ALPHA.-[2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL]-.OMEGA.-HYDROXYPOLY(OXY-1,2-ETHANEDIYL) CHLORIDE, CELLULOSE, ETHER WITH Ã [2HYDROXY3(TRIMETHYLAMMONIO)PROPYL] HYDROXYPOLY(OXY1,2ETHANEDIYL) CHLORIDE, CHLORIDE 2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL ETHER, CHLORIDE CELLULOSE, 2-HYDROXYETHYL 2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL ETHER, CHLORIDE CELLULOSE, 2-HYDROXYETHYL 23-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL ETHER, CHLORIDE CELLULOSE, 2-[2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPOXY]ETHYL ETHER, CHLORIDE CELLULOSE, 2-[2-HYDROXY-3-TRIMETHYLAMMONO)PROPOXY] ETHYL ETHER, O-[2-HYDROXY-3-(TRIMETHYLAMMONIO)PROPYL] HYDROXYETHYLCE LLULOSE CHLORIDE, POLYQAUTERNIUM-10, POLYQUATERNIUM-10, and QUATERNIUM-19
What is Polyquaterniums used for?
Group of ingredients used primarily in hair-care products for their antistatic and film-forming properties. They can have water-binding properties for skin due to the sheer “plastic” film layer they create on skin.
How Polyquaterniums is classified
Texture Enhancer
Recommendations for using Polyquaterniums during pregnancy and breastfeeding
Limited data suggests no known risk
Polyquaterniums During Pregnancy
What we know about using Polyquaterniums while pregnant or breastfeeding
Limited information available.
Reproductive/developmental toxicity data on Polyquaternium-22 or Polyquaternium-39 were not found in the published literature.
General safety info about Polyquaterniums from CIR
Polyquaternium-22 and Polyquaternium-39 function as antistatic agents, film formers, and hair fixatives in cosmetic products. According to information supplied to the Food and Drug Administration (FDA) by industry as part of the Voluntary Cosmetic Registration Program (VCRP) in 2011, both ingredients were being used in cosmetic products. Results from a survey of ingredient use concentrations provided by the Personal Care Products Council in 2011 indicate that these 2 ingredients were being used at concentrations up to 2% (Polyquaternium-22, in a rinse-off product) and up to3 % (Polyquaternium-39, in a rinse-off product). Polyquaternium-22 (MerquatTM* 280 Polymer) and polyquaternium-39 (MerquatTM PLUS 3330 Polymer) were classified as non-toxic (LD50 > 5 g/kg) in acute oral toxicity studies. Distrubted for Comment Only — Do Not Cite or Quote 6 MerquatTM* 280 Polymer and MerquatTM PLUS 3330 Polymer were classified as non-irritants when instilled into the eyes of rabbits. A 0.16% Polyquaternium-22 oxidation dye, tested at a concentration of 10% (0.016% active Polyquaternium-22) in an in vitro HET-CAM test, was classified as a slight ocular irritant. Both MerquatTM* 280 Polymer and MerquatTM PLUS 3330 Polymer were classified as non-irritants when applied, under an occlusive patch, to the skin of albino rabbits. In single and multiple application occlusive patch tests, a 0.16% olyquaternium-22 oxidation dye, tested at a concentration of 10% (0.016% active Polyquaternium-22), was not predicted to be a skin irritant in human subjects. In an HRIPT (occlusive patches), MerquatTM PLUS 3330 Polymer was classified as a non-irritant and non-sensitizer. MerquatTM* 280 Polymer, MerquatTM* 295 polymer (also polyquaternium-22), and MerquatTM PLUS 3330 Polymer were non-genotoxic in the Ames test when tested at doses up to 5,000 ¬µg/plate in the following Salmonella typhimurium strains: TA98, TA100, TA1535, and TA1537. MerquatTM* 280 Polymer and MerquatTM* 295 polymer) were also nongenotoxic in Escherichia coli strain WP2 uvr A when tested according to the same procedure. MerquatTM PLUS 3330 Polymer was not evaluated for genotoxiciy in Escherichia coli strain WP2 uvr A in this study.
Use this, not that!
Products where you might find Polyquaterniums
Moroccanoil Curl Defining Cream; Bumble and bumble Thickening Spray; REN Clean Skincare Evercalm Overnight Recovery Balm
List of References
General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/
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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.