The Basics On Pvp Copolymer
What is Pvp Copolymer?
What are other names for Pvp Copolymer?
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What is Pvp Copolymer used for?
Helps hair hold its style by inhibiting the hair’s ability to absorb moisture. VP/VA Copolymer dries to form a thin coating on the skin, hair or nails. It is also used to hold together the ingredients of a compressed tablet or cake and helps to distribute or to suspend an insoluble solid in a liquid.
How Pvp Copolymer is classified
Texture Enhancer
Recommendations for using Pvp Copolymer during pregnancy and breastfeeding
Limited data suggests no known risk
Pvp Copolymer During Pregnancy
What we know about using Pvp Copolymer while pregnant or breastfeeding
Limited information available.
In Vitro PVP No teratogenic effects were observed when up to 500 µg of PVP (MW 11,500) was injected into the yolk sac of rabbit embryos. 7 GENOTOXICITY STUDIES In Vitro Ammonium Acryloyldimethyltaurate/VP Copolymer Ammonium Acryloyldimethyltaurate/VP Copolymer was not mutagenic in bacterial reverse mutation assays.11 PVP PVP was negative in the majority of mutagenicity studies conducted. 7 The in vitro assays that were performed in these studies included Ames, mouse lymphoma, and Balb/c 3T3 tests. Three formulations containing PVP-iodine were not genotoxic in a comet assay or a chromosome aberration test, with or without metabolic activation.28 The solutions contained 3% or 10% PVP-iodine. In both tests, CHO-K1 cells were exposed for 4 h to the test solutions. Expected results were observed with positive and negative controls. The genotoxicity of PVP was evaluated in the Ames test using the following Salmonella typhimurium strains: TA98, TA100, TA1535, and TA1537.29,30 Each strain was tested with 10% PVP (in water) with and without metabolic activation. The results were classified as negative in all bacterial strains, with and without metabolic activation. Sodium Acryloyldimethyltaurate/VP Crosspolymer The genotoxicity of Sodium Acryloyldimethyltaurate/VP Crosspolymer was evaluated in the Ames test (bacterial strains and doses not stated) (Organization for Economic Co-operation and Development (OECD) Test Guideline (TG) 471).5 The test substance was classified as non-genotoxic. Triacontanyl PVP The genotoxicity of a Triacontanyl PVP trade name material was evaluated in the Ames test using the following Salmonella typhimurium strains: TA98, TA100, TA1535, TA1537, and TA1538.3 The test substance was evaluated (with and without metabolic activation) at doses up to 2500 µg/plate. 2-Aminoanthracene, 2-nitrofluorene, sodium azide, and ICR191 served as positive controls. The test substance was not genotoxic in any of the Salmonella typhimurium strains tested. Marked increases in the number of revertant colonies were observed in positive control cultures.
General safety info about Pvp Copolymer from CIR
No report found.
Use this, not that!
Products where you might find Pvp Copolymer
Bumble and bumble Thickening Dryspun Volume Texture Spray
List of References
General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/
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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.