The Basics On Rosmarinus Officinalis Extract

What is Rosmarinus Officinalis Extract?

What are other names for Rosmarinus Officinalis Extract?

EXTRACT OF ROSEMARY, EXTRACT OF ROSMARINUS OFFICINALIS, ROSEMARY CONCRETE, ROSEMARY EXTRACT, ROSEMARY LEAF EXTRACT, ROSEMARY LEAF POWDER EXTRACT, ROSEMARY, EXT., ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT, ROSMARINUS OFFICINALIS (ROSEMARY) LEAF POWDER EXTRACT, ROSMARINUS OFFICINALIS EXTRACT, ROSMARINUS OFFICINALIS LEAF EXTRACT, and ROSMARINUS OFFICINALIS LEAF POWDER EXTRACT

What is Rosmarinus Officinalis Extract used for?

How Rosmarinus Officinalis Extract is classified

Antioxidants, Plant Extracts, Fragrance: Synthetic and Fragrant Plant Extracts

Recommendations for using Rosmarinus Officinalis Extract during pregnancy and breastfeeding

Limited data suggests no known risk

 

Rosmarinus Officinalis Extract During Pregnancy

What we know about using Rosmarinus Officinalis Extract while pregnant or breastfeeding

Limited information available.

Non-Human Rosmarinus Officinalis (Rosemary) Leaf Extract Oral administration of Rosmarinus officinalis (rosemary) leaf extract adversely affected fertility in male rats.51 Groups of 10 male Sprague Dawley rats were fed diet with 0, 250 or 500 mg/kg bw/day of an ethanol extract of Rosmarinus officinalis (rosemary) leaves in distilled water. After 53 days of dosing, each male rat was mated with two untreated female rats for 10 days; the female rats had been given a subcutaneous (s.c.) dose of 5.0 mg estradiol benzoate 54 h before and 0.5 mg Distrubted for Comment Only — Do Not Cite or Quote 7 progesterone 6 h before being placed with the males. The males were dosed during, and killed after, the 10-day mating period, and the reproductive organs were examined. The females were killed 1 wk after removal of the males, and the reproductive tract of each female was examined to determine pregnancy and the number of implantation sites, viable fetuses, and fetal resorptions. The body weights of male rats of the test groups were similar to those of controls. The absolute and relative organ to body weights of the testes, epididymides, seminal vesicles, ventral prostates, and vas deferens of the high dose animals were statistically significantly reduced compared to the controls. The sperm motility in cauda epididymides, sperm density, seminiferous tubule diameter, Leydig cell nuclear diameter, and epithelial height in epididymides and seminal vesicles were also statistically significantly reduced in the animals dosed with 500 mg/kg bw/day Rosmarinus officinalis (rosemary) leaf extract. Also in the high-dose group rats, germinal cells (i.e., spermatogonia, primary and secondary spermatocytes, and spermatids) and interstitial cells (i.e., fibroblasts and immature and mature Leydig cells) were statistically significantly decreased, and degenerating cells were statistically significantly increased. Clinical chemistry parameters were also evaluated; testosterone, follicle-stimulating hormone, and luteinizing hormone levels were statistically significantly decreased in high-dose male rats. Exposure to 500 mg/kg bw Rosmarinus officinalis (rosemary) leaf extract reduced fertility; the number of pregnant females was decreased in this group, there was a statistically significant decrease in the number of implantations and viable fetuses, and the total number of resorptions was statistically significantly increased. The same trends were generally found in the rats of the low-dose groups, but the changes did not reach statistical significance. Rosmarinus Officinalis (Rosemary) Flower/Leaf/Stem Extract A group of 12 gravid female Wistar rats was dosed by gavage with 26 mg/day of a 30% aq. extract of Rosmarinus officinalis (rosemary) flower/leaf/stem extract (13 mg/ml solids) on days 1-6 of gestation (preimplantation), and a group of 14 gravid rats was dosed with the extract on days 6-15 of gestation (organogenesis).52 Negative control groups of 12 or 11 gravid rats were given saline by gavage on days 1-6 or 6-15 of gestation, respectively. All dams were killed on day 21 of gestation. No signs of maternal toxicity were observed, and maternal weight gains were similar for treated and control groups. In the rats dosed on days 1-6 of gestation, a non-statistically significant increase in preimplantation loss was observed. No changes in post-implantation loss were seen as compared to controls, and no other reproductive parameters were affected. In the group treated on days 6-15 of gestation, a non-statistically significant increase in post-implantation loss rate (2.54%) was reported; analysis of the resorptions found that they occurred during the early post-implantation period. No other changes in reproductive parameters were observed when compared to the negative control group. Developmental effects were not observed in either group. Human According to the PDR for Herbal Medicines, rosemary preparations should not be used as a drug during pregnancy.53 According to Herbal Drugs and Phytopharmaceuticals, toxic side effects may occur with components of the essential oil.54

General safety info about Rosmarinus Officinalis Extract from CIR

No report found.

Use this, not that!

Products where you might find Rosmarinus Officinalis Extract

GROWN ALCHEMIST Intensive Hand Cream – Persian Rose & Argan Extract (2.29 oz.); skyn ICELAND Icelandic Relief Eye Cream with Glacial Flower Extract (0.49 oz.);skyn ICELAND Oxygen Infusion Night Cream with Glacial Flower Extract (1.98 oz.); Bumble and bumble Sunday Clarifying Shampoo; rms beauty Luminizing & Bronzing Powders

 

 

 

List of References

General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/

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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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