The Basics On Sodium Ascorbate
What is Sodium Ascorbate?
What are other names for Sodium Ascorbate?
L-ASCORBIC ACID, MONOSODIUM SALT, LASCORBIC ACID, MONOSODIUM SALT, MONOSODIUM SALT L-ASCORBIC ACID, SODIUM ASCORBATE, and VITAMIN C SODIUM
What is Sodium Ascorbate used for?
Vitamin C, also known as L-ascorbic acid, is a water-soluble, unstable vitamin that is the main antioxidant compound for our skin. It is a vital component of our skin structure and function. Topical vitamin C has a wide range of clinical applications, from antiaging and anti-pigmentation to skin photoprotection1 as well as being a known enhancer of skin collagen and elastin production. Humans, unlike most animals, are unable to synthesize vitamin C endogenously, so it is an essential dietary component. It can be successfully applied topically to our skin to deliver significant benefits
How Sodium Ascorbate is classified
Antioxidants, Vitamins
Recommendations for using Sodium Ascorbate during pregnancy and breastfeeding
Limited data suggests no known risk
Sodium Ascorbate During Pregnancy
What we know about using Sodium Ascorbate while pregnant or breastfeeding
Limited information available.
N/A
General safety info about Sodium Ascorbate from CIR
No report found.
Use this, not that!
Products where you might find Sodium Ascorbate
SOBEL SKIN Rx 35% Vitamin C Face Serum
List of References
General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/
1. Al-Niaimi F, Chiang N. Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications. J Clin Aesthet Dermatol. 2017;10(7):14-17. [PubMed] 2. Hinek A, Kim H, Wang Y, Wang A, Mitts T. Sodium L-ascorbate enhances elastic fibers deposition by fibroblasts from normal and pathologic human skin. J Dermatol Sci. 2014;75(3):173-182. [PubMed] 3. Traikovich S. Use of topical ascorbic acid and its effects on photodamaged skin topography. Arch Otolaryngol Head Neck Surg. 1999;125(10):1091-1098. [PubMed] 4. Pinnell S, Yang H, Omar M, et al. Topical L-ascorbic acid: percutaneous absorption studies. Dermatol Surg. 2001;27(2):137-142. [PubMed] 5. Chen L, Hu J, Wang S. The role of antioxidants in photoprotection: a critical review. J Am Acad Dermatol. 2012;67(5):1013-1024. [PubMed] 6. Moores J. Vitamin C: a wound healing perspective. Br J Community Nurs. 2013;Suppl:S6, S8-11. [PubMed] 7. Lin J, Selim M, Shea C, et al. UV photoprotection by combination topical antioxidants vitamin C and vitamin E. J Am Acad Dermatol. 2003;48(6):866-874. [PubMed] 8. Lin F, Lin J, Gupta R, et al. Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. J Invest Dermatol. 2005;125(4):826-832. [PubMed] 9. Gönüllü U, Yener G, Uner M, Incegül T. Moisturizing potentials of ascorbyl palmitate and calcium ascorbate in various topical formulations. Int J Cosmet Sci. 2004;26(1):31-36. [PubMed] 10. Uchida Y, Behne M, Quiec D, Elias P, Holleran W. Vitamin C stimulates sphingolipid production and markers of barrier formation in submerged human keratinocyte cultures. J Invest Dermatol. 2001;117(5):1307-1313. [PubMed] 11. Kim K, Shin K, Park K, et al. Vitamin C Stimulates Epidermal Ceramide Production by Regulating Its Metabolic Enzymes. Biomol Ther (Seoul). 2015;23(6):525-530. [PubMed] 12. Shimada Y, Tai H, Tanaka A, et al. Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo. J Periodontol. 2009;80(2):317-323. [PubMed] 13. Panich U, Tangsupa-a-nan V, Onkoksoong T, et al. Inhibition of UVA-mediated melanogenesis by ascorbic acid through modulation of antioxidant defense and nitric oxide system. Arch Pharm Res. 2011;34(5):811-820. [PubMed] 14. Kishimoto Y, Saito N, Kurita K, Shimokado K, Maruyama N, Ishigami A. Ascorbic acid enhances the expression of type 1 and type 4 collagen and SVCT2 in cultured human skin fibroblasts. Biochem Biophys Res Commun. 2013;430(2):579-584. [PubMed] 15. Humbert P, Haftek M, Creidi P, et al. Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo. Exp Dermatol. 2003;12(3):237-244. [PubMed] 16. Herndon J, Jiang L, Kononov T, Fox T. An Open Label Clinical Trial to Evaluate the Efficacy and Tolerance of a Retinol and Vitamin C Facial Regimen in Women With Mild-to-Moderate Hyperpigmentation and Photodamaged Facial Skin. J Drugs Dermatol. 2016;15(4):476-482. [PubMed] 17. Burgess C. Topical vitamins. J Drugs Dermatol. 2008;7(7 Suppl):s2-6. [PubMed] 18. Elmore A. Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics. Int J Toxicol. 2005;24 Suppl 2:51-111. [PubMed] 19. Wang K, Jiang H, Li W, Qiang M, Dong T, Li H. Role of Vitamin C in Skin Diseases. Front Physiol. 2018;9:819. [PubMed] 20. Gallarate M, Carlotti M, Trotta M, Bovo S. On the stability of ascorbic acid in emulsified systems for topical and cosmetic use. Int J Pharm. 1999;188(2):233-241. [PubMed]
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
