Synthetic Beeswax

The Basics On Synthetic Beeswax

What is Synthetic Beeswax?

An artificial form of beeswax.

What are other names for Synthetic Beeswax?

BEESWAX, SYNTHETIC, MIXED WAX, and SYNTHETIC BEESWAX

What is Synthetic Beeswax used for?

The properties of Synthetic Beeswax resemble beeswax. Safety Information: … The CIR Expert Panel evaluated the scientific data and concluded that Ozokerite, Ceresin, Montan Wax, Paraffin, Microcrystalline Wax, Emulsifying Wax, Synthetic Wax and Synthetic Beeswax were safe for use in cosmetics and personal care products.

How Synthetic Beeswax is classified

Thickeners/Emulsifiers, Emollients

Recommendations for using Synthetic Beeswax during pregnancy and breastfeeding

Limited data suggests no known risk

 

Synthetic Beeswax During Pregnancy

What we know about using Synthetic Beeswax while pregnant or breastfeeding

Limited information available.

A safety assessment of Dibutyl Phthalate (DBP), Diethyl Phthalate (DEP), and Dimethyl Phthalate (DMP) was published in 1985 with the conclusion that these ingredients “are safe for topical application in the present practices of use and concentrations in cosmetics” (Elder 1985). Since then many additional studies have appeared in the scientific literature. These studies, along with the updated information in Table 8 regarding uses and use concentrations, were considered by the CIR Expert Panel. Based on its consideration of the data discussed below, the Panel decided not to reopen this safety assessment. DBP, DEP, and DMP are phthalate diesters that are used in cosmetics as plasticizers, solvents and fragrance ingredients in a wide variety of cosmetic product types. DEP is also used as a denaturant. DBP is found primarily in nail care products (at concentrations up to 15%) and in some hair care formulations (up to 0.1%). DEP is found in certain bath preparations, fragrance products, deodorants, lotions, and other skin care products. The highest reported concentration of use of DEP is 11% in perfumes. DMP is an ingredient in some hair care products, including aerosol fixatives. The reported maximum concentration of use of DMP in cosmetics is 2% in aerosol hair sprays. Table 8 provides the frequency and concentration of use as a function of product type. Recent studies document that DBP, DEP, and DMP all absorb readily through the skin and through the gastrointestinal (GI) tract. Once absorbed, most short-chain phthalate diesters are hydrolyzed to the corresponding monoester and alcohol. The phthalates and their metabolites distribute to most tissues, and cross the placenta, but they do not accumulate in any specific tissue type. Phthalates are quickly eliminated in the urine, usually as the corresponding monoester or its glucuronide conjugate. However, humans and primates metabolize longer-chain diester phthalates (e.g., DEHP) into the glucuronide-conjugated monoester forms to a much larger extent than do rats. Also, rats excrete three to four times more free unconjugated MBP than do hamsters given similar doses of DBP or MBP, possibly due to greater testicular β-glucuronidase activity in rats than in hamsters. Phthalates undergo some enterohepatic cycling, and some phthalate is eliminated in the feces. New data on acute and short-term toxicity were consistent with previously available data. In a NTP study, DBP, DEP, and DMP were not found to be dermal irritants or sensitizers, confirming previous data using human and animal subjects. Although previous data had identified that orally administered (in feed or by gavage) DBP and its metabolite MBP have reproductive and developmental effects in rodents, with impaired male development being the most sensitive effect, newly available data provided additional demonstration of such effects. When pregnant rats and mice were exposed to 1.0% DBP in powdered feed throughout gestation, the pregnancy outcome showed reductions in fertility, number of pups per litter, number of live pups, and body weights of pups. Adult male rats exposed to 1.0% DBP showed signs of liver and kidney toxicity and reduced weights of the prostate, testes, and seminal vesicles. Pregnant rats exposed to 2% DBP in feed throughout pregnancy had a higher incidence of preimplantation loss and resorptions, and no male pups were born alive. Exposure to 1% or 2% DBP in feed only during the latter half of gestation did not show the preimplantation loss and resorption rate seen in rats exposed throughout pregnancy. However, the increased survivability of these fetuses allowed the morphological defects of developing fetuses to be observed. These defects included reduced body weights in both sexes at 2% DBP, reduced anogenital distance and undescended testes in male fetuses at 1% and 2% DBP, and increased incidence of cleft palate and fused sternebrae. Adverse fetal effects were not seen in this study in a 0.5% DBP feed group, or at 331 mg/kg/day, based on average food consumption. Oral intubation (gavage) of DBP in rats during gestation produced similar effects to those seen in the feeding studies described above. Pregnant rats given oral doses of approximately 0.63 to 0.75 g/kg/day and higher on certain gestation days produced litters with higher incidences of fetal toxicity and malformations. Exposure to DBP on gestation days 7 through 9 or on days 13 through 15 results in increased incidence of skeletal malformations such as cleft palate, fused sternebrae, and vertebral anomalies, as well as dilatation of the renal pelvis and undescended testes. However, exposure to DBP on gestation days 10 through 12 did not produce these effects, suggesting that DBP teratogenicity may be age dependent. Prenatal exposure to MBP appears to produce fetotoxicity and teratogenicity similar to DBP, following the same patterns of age-dependent sensitivity and dose efficacy. This supports the proposal that it is the monoester metabolite that produces the developmental toxicity of DBP and other phthalates. DEP fed to mice at concentrations up to 2.5% (calculated to be 3.64 g/kg/day) in a continuous breeding protocol produced no effects of DEP on fertility or pregnancy outcome in the F0 generation. F1 male mice of the 2.5% DEP group had enlarged prostates and reduced sperm counts, but sperm motility and morphology were not affected. The F2 generation showed no treatment-related differences between DEP and control groups. Pregnant rats fed up to 5.0% DEP mixed in feed on gestation days 6 through 15 produced no treatment-related alterations in fetal viability or development. Repeated dermal application of 2 ml/kg up to 50% DEP to pregnant rabbits on gestation days 6 through 18 did not produce maternal or fetal toxicity or affect fetal development. DMP was not fetotoxic or teratogenic when administered dermally (in rats) or orally (in rats and mice) during gestation.

General safety info about Synthetic Beeswax from CIR

The Cosmetic Ingredient Review (CIR) program Expert Panel has assessed the safety of almost 1200 cosmetic ingredients since its inception in 1976. The very first safety assessments were published in earlier incarnations of this journal‚Äîthe Journal of Environmental Pathology and Toxicology in 1980, and the Journal of the American College of Toxicology from 1982 to 1996. Because information relevant to the safety of ingredients may have become available since these early safety assessments were published, the CIR Expert Panel has initiated a re-review process. If new information is thought to be available or if a long period of time has passed, the CIR Expert Panel may initiate a search for relevant new data. In some cases, newly available data are largely redundant with the data available in the original safety assessment. In other cases, there are new safety data. If after considering the newly available information, the CIR Expert Panel decides not to reopen a safety assessment, this finding, along with any background material, is summarized and announced publicly. To assure that the scientific community is aware of any new information and the decision not to reopen, this Annual Review of Cosmetic Ingredient Safety Assessments is prepared. This annual review covers all ingredients re-reviewed from February, 2002, to June, 2003. For each original safety assessment the re-review addresses the import of new studies that were considered by the Panel, if any were available. A reference list is provided that updates the references provided in the original safety assessment. The re-review also captures information on the industry’s current practices of ingredient use, updating the data available in the earlier report. Although this material provides the opinion of the CIR Expert Panel regarding the new data described, it does not constitute a full safety review. The ingredients the CIR Expert Panel reconsidered in 2002/ 2003, and decided not to reopen are:

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Products where you might find Synthetic Beeswax

Anastasia Beverly Hills Lash Brag Volumizing Mascara