The Basics On Tocotrienols

What is Tocotrienols?

Potent forms of vitamins E that are considered stable and powerful antioxidants.

What are other names for Tocotrienols?

TOCOTRIENOLS

What is Tocotrienols used for?

Although less studied than tocopherols (approximately one percent of the literature on vitamin E addresses tocotrienols), tocotrienols have been reported to act as stronger antioxidants but have exhibit lower bioavailability1. The tocotrienol forms of natural vitamin E possesses powerful hypocholesterolemic, anti-cancer and neuroprotective properties that are often not exhibited by tocopherols. To date, there has only been 1% of the research literature on vitamin E that has nee devoted to tocotrienol1. Much more work needs to be conducted on the effectiveness of tocotrienol and its biological functions to better assess it’s benefits to our skin2.

How Tocotrienols is classified

Antioxidants, Vitamins

Recommendations for using Tocotrienols during pregnancy and breastfeeding

Limited data suggests no known risk

 

Tocotrienols During Pregnancy

What we know about using Tocotrienols while pregnant or breastfeeding

Limited information available.

Oral administration of tocopherol ((up to 75 mg /day in the diet), tocopheryl succinate, and tocophersolan did not have reprodu-ctive or developmental effects in rats, and tocopheryl acetate (≤ 1.6 g/kg/day) generally did not have any reproductive or devel-opmental effects in rabbits, hamsters, rats, or mice. Tocopherol and tocopheryl acetate had some effect on reducing the number of malformations observed in neonates from diabetic dams. Tocopherol did not have an effect on zinc deficiency-induced terato-genicity. In some studies, tocopheryl acetate potentiated the embryo-lethal effects of cortisone acetate. Tocopheryl succinate reduced some reproductive effects, but not all, induced by TCDD.1

General safety info about Tocotrienols from CIR

The Expert Panel assessed the safety of 14 tocopherols and tocotrienols, and concluded these ingredients are safe as used in cosmetics. The tocopherols are reported to function in cosmetics as antioxidants or skin conditioning agents; in contrast, tocotrienols is not reported to function as an anti-oxidant in cosmetics, but as a light stabilizer, oral care agent, or skin conditioning agent. The Panel reviewed the new and exist-ing animal and clinical data to determine the safety of these ingredients in determining safety, and found it appropriate to extrapolate the existing information to conclude on the safety of all the tocopherols and tocotrienols.

Use this, not that!

Products where you might find Tocotrienols

Drunk Elephant Virgin Marula Antioxidant Face Oil Mini; Eve Lom Age Defying Smoothing Treatment; only 2 products listed

 

 

 

List of References

General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/

1. Sen C, Khanna S, Roy S. Tocotrienols in health and disease: the other half of the natural vitamin E family. Mol Aspects Med. 2007;28(5-6):692-728. [PubMed] 2. Sen C, Khanna S, Roy S. Tocotrienols: Vitamin E beyond tocopherols. Life Sci. 2006;78(18):2088-2098. [PubMed] 3. Fiume M, Bergfeld W, Belsito D, et al. Safety Assessment of Tocopherols and Tocotrienols as Used in Cosmetics. Int J Toxicol. 2018;37(2_suppl):61S-94S. [PubMed] Related Articles: Glossary: Alpha tocopherol Glossary: Vitamin E Glossary: Elaeis Guineensis (Palm) Oil Glossary: Oryza Sativa (Rice Bran) Oil

 

 

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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