The Basics On Vitamin A

What is Vitamin A?

What are other names for Vitamin A?

3,7-DIMETHYL-9-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-2,4,6,8-NONATETRAEN-1-OL, DRY FORMED VITAMIN A, RETINOL, RETINOL (VITAMIN A), and VITAMIN A

What is Vitamin A used for?

produce less skin water loss, skin itching, irritation and scaling than retinoic acid1 inhibit UV induction in the skin to prevent skin photoaging8 stimulate collagen synthesis and fibroblast growth in photoaged skin9 reduce the appearance of fine wrinkles in aged and photoaged skin10 when used topically in conjunction with vitamin C partially reverse the skin changes induced by both chronological and photoaging11 reduce the incidence of acne by helping unclog skin pores that lead to acne formation12 and can have anti-inflammatory benefits for acne treatment12 Retinol cream at 1% concentration of vitamin A used over a 12 week period showed fibroblast growth, collagen synthesis and significant improvement in fine wrinkles9. Retinol cream at 0.25% does not irritate the skin but can induce similar antiaging changes as that of retinoic acid at 0.025%7.

How Vitamin A is classified

Antioxidants, Vitamins

Recommendations for using Vitamin A during pregnancy and breastfeeding

Is it OK to take vitamin A while pregnant? Avoid

Vitamin A During Pregnancy

What we know about using Vitamin A while pregnant or breastfeeding

Can you take vitamin A during pregnancy? Limited information available.

General safety info about Vitamin A from CIR

No report found.

Use this, not that!

Coming soon!

Products where you might find Vitamin A

Sunday Riley C.E.O. Glow Vitamin C + Turmeric Face Oil, Sunday Riley C.E.O. 15% Vitamin C Brightening Serum, Sunday Riley C.E.O. Vitamin C Rich Hydration Cream,Sunday Riley C.E.O. Glow Vitamin C + Turmeric Face Oil, Vichy LiftActiv Vitamin C Serum Brightening Skin Correcto; Drunk Elephant C-Firma Vitamin C Day Serum, Murad Multi-Vitamin Infusion Oil, Tata Harper Retinoic Nutrient Face Oil With Vitamin A, CLINIQUE Fresh Pressed Clinical Daily + Overnight Boosters with Pure Vitamin C 10% + A (Retinol), Alpha-H Vitamin A Serum with 0.5% Retinol

List of References

General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/

1. Mukherjee S, Date A, Patravale V, Korting H, Roeder A, Weindl G. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clin Interv Aging. 2006;1(4):327-348. [PubMed] 2. Antille C, Tran C, Sorg O, Saurat J. Penetration and metabolism of topical retinoids in ex vivo organ-cultured full-thickness human skin explants. Skin Pharmacol Physiol. 2004;17(3):124-128. [PubMed] 3. Bendich A, Olson J. Biological actions of carotenoids. FASEB J. 1989;3(8):1927-1932. [PubMed] 4. Roos T, Jugert F, Merk H, Bickers D. Retinoid metabolism in the skin. Pharmacol Rev. 1998;50(2):315-333. [PubMed] 5. Sorg O, Antille C, Kaya G, Saurat J. Retinoids in cosmeceuticals. Dermatol Ther. 2006;19(5):289-296. [PubMed] 6. Tran C, Sorg O, Carraux P, Didierjean L, Saurat J. Topical delivery of retinoids counteracts the UVB-induced epidermal vitamin A depletion in hairless mouse. Photochem Photobiol. 2001;73(4):425-431. [PubMed] 7. Duell E, Kang S, Voorhees J. Unoccluded retinol penetrates human skin in vivo more effectively than unoccluded retinyl palmitate or retinoic acid. J Invest Dermatol. 1997;109(3):301-305. [PubMed] 8. Fisher G, Datta S, Talwar H, et al. Molecular basis of sun-induced premature skin ageing and retinoid antagonism. Nature. 1996;379(6563):335-339. [PubMed] 9. Varani J, Warner R, Gharaee-Kermani M, et al. Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin. J Invest Dermatol. 2000;114(3):480-486. [PubMed] 10. Pi√©rard-Franchimont C, Castelli D, Cromphaut I. Tensile properties and contours of aging facial skin, A controlled double-blind comparative study of the effects of retinol, melibose-lactose and their association. Skin Res Technol. 1998;(4):237-243. 11. Seit√© S, Bredoux C, Compan D, et al. Histological evaluation of a topically applied retinol-vitamin C combination. Skin Pharmacol Physiol. 2005;18(2):81-87. [PubMed] 12. Thielitz A, Abdel-Naser M, Fluhr J, Zouboulis C, Gollnick H. Topical retinoids in acne‚Äìan evidence-based overview. J Dtsch Dermatol Ges. 2008;6(12):1023-1031. [PubMed] 13. Retinol. EWG’s Skin Deep Cosmetic Database. https://www.ewg.org/skindeep/ingredient/706889/RETINOL_%28VITAMIN_A%29/#. Published 2018. Accessed October 2018.

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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