The Basics On Xylitylglucoside

What is Xylitylglucoside?

An ingredient derived from two water-binding plant sugars, xylitol and glucose.

What are other names for Xylitylglucoside?

XYLITYLGLUCOSIDE

What is Xylitylglucoside used for?

An ingredient derived from two water-binding plant sugars, xylitol and glucose. Its trade name is Aquaxyl. It works to improve skin moisturization by preventing water loss.

How Xylitylglucoside is classified

Hydration

Recommendations for using Xylitylglucoside during pregnancy and breastfeeding

Limited data suggests no known risk

 

Xylitylglucoside During Pregnancy

What we know about using Xylitylglucoside while pregnant or breastfeeding

Limited information available.

No adverse effects on fertility or reproductive performance were observed in a study in which male and female Wistar rats were dosed orally with up to 500 mg/kg bw Hydroxydecyl Ubiquinone prior to mating, during gestation, and until day 22 post-partum. 47 In several other studies, no statistically significant adverse effects upon reproductive performance or fetal development were seen in rats dosed at up to 1000 mg/kg/d Hydroxydecyl Ubiquinone, although a higher incidence of postimplantation loss was reported in some studies. 3,4 The NOAELs, based on body surface area comparisons, were determined to be up to 1000 mg/kg/d for embryofetal development, and 500 mg/kg/d and 1000 mg/kg/d, for male and female fertility, respectively. 4 Rabbits, dosed at up to 150 mg/kg/d Hydroxydecyl Ubiquinone and observed for teratological abnormalities, displayed chromaturia in the highest dosage group. 3 In Japanese rabbits dosed at up to 500 mg/kg/d Hydroxydecyl Ubiquinone, one abortion was observed in the highest dosage group, but was not considered significant due to the spontaneous abortion rate in the animal strain; no statistically significant embryofetal differences were reported between controls and treated groups.4 No treatment-related changes were observed in the F1 generation, or in the dams, of rats dosed at up to 500 mg/kg/d Hydroxydecyl Ubiquinone. 3,4 The NOAEL for rat pup development was determined to be 500 mg/kg/d Hydroxydecyl Ubiquinone. 4 Treatment with Ubiquinone had no effect on fetal death, weight, or postnatal toxicity in primigravid mice (strain and number not specified) dosed at up to 600 mg/kg/d, from day 7 to day 13 of gestation. 30 Groups of 10 male mice were given up to 10,000 mg/kg bw Ubiquinone, via gavage, for 5 d, followed by a 35-d latency period, to test for defects in sperm morphology.49 No significant differences were found in the incidence of sperm abnormalities between Ubiquinone-treated mice and the negative controls (treated with corn oil). Except for an increase in seminiferous epithelium heights, no biochemical, histological, or morphological differences were observed between 8 male Wistar rats dosed at 10 mg/kg bw/d Ubiquinone for 14 d and negative control and vehicle control groups.51 Treatment with Ubiquinone had no effect on fetal death, weight, or postnatal activity in primigravid rats dosed at up to 600 mg/kg/d, from day 9 to day 15 of gestation. 30

General safety info about Xylitylglucoside from CIR

No report found.

Use this, not that!

Products where you might find Xylitylglucoside

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List of References

General sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/

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Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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