Zinc Sulfate

The Basics On Zinc Sulfate

What is Zinc Sulfate?

Chemical compound resulting from the interaction of zinc with sulfuric acid.

What are other names for Zinc Sulfate?

SULFURIC ACID, ZINC SALT, SULFURIC ACID, ZINC SALT (1:1), SULFURIC ACID, ZINC SALT (1:1); ZINC SULFATE, ZINC SALT SULFURIC ACID, ZINC SULFATE, and ZINC SULPHATE

What is Zinc Sulfate used for?

Zinc Sulfate is a colorless crystalline compound. In cosmetics and personal care products, Zinc Sulfate is used in the formulation of bath products, skin fresheners and cleansers and skin care products. Zinc Sulfate functions as a cosmetic astringent , a cosmetic biocide and as an oral care agent .

How Zinc Sulfate is classified

Preservatives, Sensitizing

Recommendations for using Zinc Sulfate during pregnancy and breastfeeding

Avoid

 

Zinc Sulfate During Pregnancy

What we know about using Zinc Sulfate while pregnant or breastfeeding

Limited information available.

Zinc is a very important element in the reproductive cycle of numerous species.99 In humans, it is necessary for the formation and maturation of spermatozoa, for ovulation, and for fertilization. During pregnancy, zinc deficiency causes a number of anomalies: spontaneous abortion, pregnancy-related toxemia, extended pregnancy or prematurity, malformations, and retarded growth. Also, delivery is adversely affected by deficiency. Provided below is a summary of DART studies that are presented in detail in Table 12. Mice were given 500 or 1000 mg/l Zinc Acetate (149 or 298 mg/l as free zinc) in the drinking water from mating through weaning; a lowest-observable-adverse-effect-level (LOAEL) of 136 mg/kg/day zinc in male and female mice was reported due to an increase in direct plaque-forming activity of spleen cells and an increase in lymphocyte proliferation with mitogen stimulation in the offspring. 24 In rats dosed by gavage with up to 30 mg/kg/day aq. Zinc Chloride (14 mg/kg/day of free zinc) for 84 days (premating through lactation), adverse effects were reported in the dams and the offspring, including a reduced number of live pups/litter, a decreased live birth index, increased mortality, and increased fetal resorption. 100 In a two-generation reproduction toxicity study in which rats were dosed by gavage daily with up to 30 mg/kg/day aq. Zinc Chloride (14 mg/kg/day of free zinc), the overall no-observed-adverse-effect-level (NOAEL) was 7.5 mg/kg/day for the F1 generation (3.6 mg/kg/day of free zinc) . 25,101 Parental animals from F0 and F1 generations had reduced fertility and viability, and effects on organ weights were reported in parental animals; reduced body weights were reported for F1 and F2 pups in 30 mg/kg/day group (14 mg/kg/day of free zinc), however no effects on weaning index, sex ratio, or litter size observed. The developmental and reproductive effects of Zinc Sulfate were examined in mice (≤ 30 mg/kg/day, or ≤ 6.8 mg/kg/day as free zinc (assuming the heptahydrate); days 6-15 of gestation), 21 rats (up to 42.5 mg/kg, or ≤ 9.7 mg/kg/day as free zinc; days 6-15 of gestation), 102 hamsters (≤ 88 mg/kg/day, or ≤ 35.6 mg/kg/day of free zinc; days 6-10 of gestation), 20,31 and rabbits (≤ 60 mg/kg, or ≤ 13.6 mg/kg/day as free zinc; days 6-18 of gestation);102 no developmental effects were observed. In studies in which male rats were fed a diet containing 4000 ppm zinc as Zinc Sulfate, 21,103 there was a decrease in the conception rate, and a statistically significantly lower number of live births per mated female. In a study in which female rats were fed a diet containing 4000 ppm zinc as Zinc Sulfate, a decrease in the conception rate was reported when the animals were dosed from the first day of conception through study termination, but not in the group that were dosed 21-26 days prior to dosing, through day 18 of gestation; there were no other statistically significant effects on reproductive parameters.104

General safety info about Zinc Sulfate from CIR

The Cosmetic Ingredient Review (CIR) Expert Panel assessed the safety of 27 inorganic and organometallic zinc salts as used in cosmetic formulations; these salts are specifically of the 2+ (II) oxidation state cation of zinc. These ingredients included in this report have various reported functions in cosmetics, including hair conditioning agents, skin conditioning agents, cosmetic astringents, cosmetic biocides, preservatives, oral care agents, buffering agents, bulking agents, chelating agents, and viscosity increasing agents. The Panel reviewed the relevant data for these ingredients, and concluded that these 27 ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be nonirritating.

Use this, not that!

Coming soon!

Products where you might find Zinc Sulfate

Credentials Clinical System Azu-Zinc Soothing Masque (2 oz.); DermaQuest SheerZinc SPF 30 Tinted – Nude (2 oz.);DermaQuest SheerZinc SPF 30 Tinted – Sunkissed (2 oz.); The Ordinary Niacinamide 10% + Zinc 1%; Biossance Squalane + Zinc Sheer Mineral Sunscreen SPF 30 PA +++; Indie Lee Banish Stick