Cefdinir

The Basics

What is Cefdinir?

Direct-acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C.

Brand names for Cefdinir

Omnicef

How Cefdinir is classified

Anti-Infective Agents, Antibacterial Agents, Cephalosporins

Cefdinir During Pregnancy

Cefdinir pregnancy category

Category BNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Cefdinir while pregnant

Cefdinir was not teratogenic in rats at oral doses up to 1000 mg/kg/day (70 times the human dose based on mg/kg/day, 11 times based on mg/m²/day) or in rabbits at oral doses up to 10 mg/kg/day (0.7 times the human dose based on mg/kg/day, 0.23 times based on mg/m²/day). Maternal toxicity (decreased body weight gain) was observed in rabbits at the maximum tolerated dose of 10 mg/kg/day without adverse effects on offspring. Decreased body weight occurred in rat fetuses at ≥ 100 mg/kg/day, and in rat offspring at ≥ 32 mg/kg/day. No effects were observed on maternal reproductive parameters or offspring survival, development, behavior, or reproductive function. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.

Taking Cefdinir While Breastfeeding

What are recommendations for lactation if you're taking Cefdinir?

Although no information is available on the use of cefdinir during breastfeeding, cephalosporins are generally not be expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant’s gastrointestinal flora, resulting in diarrhea or thrush have been reported with cephalosporins, but these effects have not been adequately evaluated. Cefdinir is acceptable in nursing mothers.

Maternal / infant drug levels

Although no information is available on the use of cefdinir during breastfeeding, cephalosporins are generally not be expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant’s gastrointestinal flora, resulting in diarrhea or thrush have been reported with cephalosporins, but these effects have not been adequately evaluated. Cefdinir is acceptable in nursing mothers.

Possible effects of Cefdinir on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Cefdinir

Ceftibuten.