The Basics

What is Ezetimibe?

Used to reduce the amount of cholesterol and other fatty substances in the blood.

Brand names for Ezetimibe

Zetia

How Ezetimibe is classified

Anticholesteremic Agents, Antilipemic Agents

Ezetimibe During Pregnancy

Ezetimibe pregnancy category

Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Ezetimibe while pregnant

N/A

Taking Ezetimibe While Breastfeeding

What are recommendations for lactation if you're taking Ezetimibe?

No relevant published information exists on the use of ezetimibe during breastfeeding. Because of a concern with disruption of infant lipid metabolism, ezetimibe is best avoided during breastfeeding. An alternate drug is preferred, especially while nursing a newborn or preterm infant. Ezetimibe treatment in combination with a statin (e.g., atorvastatin, simvastatin) should be avoided in nursing mothers.

Maternal / infant drug levels

No relevant published information exists on the use of ezetimibe during breastfeeding. Because of a concern with disruption of infant lipid metabolism, ezetimibe is best avoided during breastfeeding. An alternate drug is preferred, especially while nursing a newborn or preterm infant. Ezetimibe treatment in combination with a statin (e.g., atorvastatin, simvastatin) should be avoided in nursing mothers.

Possible effects of Ezetimibe on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Ezetimibe

Cholestyramine, Colesevelam, Colestipol.

List of References

Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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