The Basics
What is Lorlatinib?
Used to treat a certain type of non-small cell lung cancer (NSCLC) that has spread to other parts of the body and has worsened after treatment with other chemotherapy medications.
Brand names for Lorlatinib
Lorbrena
How Lorlatinib is classified
Enzyme Inhibitors, Protein Kinase Inhibitors, Signal Transduction Inhibitors, Tyrosine Kinase Inhibitors
Lorlatinib During Pregnancy
Lorlatinib pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Lorlatinib while pregnant
N/A
Taking Lorlatinib While Breastfeeding
What are recommendations for lactation if you're taking Lorlatinib?
No information is available on the clinical use of lorlatinib during breastfeeding. The manufacturer recommends that breastfeeding be discontinued during lorlatinib therapy and for 7 days after the last dose.
Maternal / infant drug levels
No information is available on the clinical use of lorlatinib during breastfeeding. The manufacturer recommends that breastfeeding be discontinued during lorlatinib therapy and for 7 days after the last dose.
Possible effects of Lorlatinib on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Lorlatinib
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
