The Basics

What is Empagliflozin?

Used to lower blood sugar levels in people with type 2 diabetes.

Brand names for Empagliflozin

N/A

How Empagliflozin is classified

Hypoglycemic Agents, Sodium-Glucose Cotransporter 2 Inhibitors, SGLT2 Inhibitors

Empagliflozin During Pregnancy

Empagliflozin pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Empagliflozin while pregnant

N/A

Taking Empagliflozin While Breastfeeding

What are recommendations for lactation if you're taking Empagliflozin?

No information is available on the clinical use of empagliflozin during breastfeeding. Empagliflozin is an uncharged molecule that is 86% protein bound in plasma, so it is unlikely to pass into breastmilk in clinically important amounts. The manufacturer does not recommend empagliflozin during breastfeeding because of a theoretical risk to the infant’s developing kidney. An alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Maternal / infant drug levels

No information is available on the clinical use of empagliflozin during breastfeeding. Empagliflozin is an uncharged molecule that is 86% protein bound in plasma, so it is unlikely to pass into breastmilk in clinically important amounts. The manufacturer does not recommend empagliflozin during breastfeeding because of a theoretical risk to the infant’s developing kidney. An alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Possible effects of Empagliflozin on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Empagliflozin

Acarbose, Glipizide, Glyburide, Insulin, Metformin, Miglitol.

List of References

Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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