The Basics
What is Trichlormethiazide?
Used in the treatment of edema (including that associated with heart failure) and hypertension.
Brand names for Trichlormethiazide
Aquacot
How Trichlormethiazide is classified
Antihypertensive Agents, Thiazide Diuretics
Trichlormethiazide During Pregnancy
Trichlormethiazide pregnancy category
Category B
Note that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Trichlormethiazide while pregnant
Trichlormethiazide falls into category B: There are no well-done studies that have been done in humans with Trichlormethiazide. But in animal studies, pregnant animals were given this medication, and the babies did not show any medical issues related to this medication. OR In animal studies, pregnant animals were given Trichlormethiazide, and some babies had problems. But in human studies, pregnant women were given this medication and their babies did not have any problems related to this medication.
Taking Trichlormethiazide While Breastfeeding
What are recommendations for lactation if you're taking Trichlormethiazide?
No information is available on the amount of trichlormethiazide in breastmilk. Intense diuresis with large doses may decrease breastmilk production. Other diuretics in low doses are preferred over trichlormethiazide.
Maternal / infant drug levels
No information is available on the amount of trichlormethiazide in breastmilk. Intense diuresis with large doses may decrease breastmilk production. Other diuretics in low doses are preferred over trichlormethiazide.
Possible effects of Trichlormethiazide on milk supply
Relevant published information on trichlormethiazide was not found as of the revision date. Intense diuresis with thiazides and thiazide-like diuretics, fluid restriction and breast binding have been used to suppress postpartum lactation.[1][2][3] The added contribution of the diuretic to these measures, which are effective in suppressing lactation, has not been studied. There are no data on the effects of diuretics on established, ongoing lactation.
Possible alternatives to Trichlormethiazide
Chlorothiazide, Hydrochlorothiazide.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/
1. Healy M. Suppressing lactation with oral diuretics. Lancet. 1961;277:1353-4.
2. Stout G. Suppression of lactation. Br Med J. 1962;1:1150. Letter. PMC: PMC1958377
3. Reiher KH. [Suppression of lactation by stimulation of diuresis]. Zentralbl Gynakol. 1963;85:188-90. PMID: 13973786
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
