Alectinib

The Basics

What is Alectinib?

Blocks the activity of anaplastic lymphoma kinase and is used to treat non-small-cell lung cancer.

Brand names for Alectinib

Alecensa

How Alectinib is classified

Antineoplastic Agents, Enzyme Inhibitors, Protein Kinase Inhibitors, Signal Transduction Inhibitors, Tyrosine Kinase Inhibitors

Alectinib During Pregnancy

Alectinib pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Alectinib while pregnant

N/A

Taking Alectinib While Breastfeeding

What are recommendations for lactation if you're taking Alectinib?

No information is available on the clinical use of alectinib during breastfeeding. Because alectinib is more than 99% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is about 33 hours and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during alectinib therapy and for 1 week after the last dose.

Maternal / infant drug levels

No information is available on the clinical use of alectinib during breastfeeding. Because alectinib is more than 99% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is about 33 hours and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during alectinib therapy and for 1 week after the last dose.

Possible effects of Alectinib on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Alectinib

None listed