The Basics

What is Baricitinib?

moderately to severely active rheumatoid arthritis who have an inadequate response to one or more tumor necrosis factor (TNF) antagonist therapies

Brand names for Baricitinib

Olumiant

How Baricitinib is classified

Antirheumatic Agents, Enzyme Inhibitors, Janus Kinase Inhibitors,, Signal Transduction Inhibitors, Protein Kinase Inhibitors

Baricitinib During Pregnancy

Baricitinib pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Baricitinib while pregnant

N/A

Taking Baricitinib While Breastfeeding

What are recommendations for lactation if you're taking Baricitinib?

No information is available on the use of baricitinib during breastfeeding. Until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. The manufacturer recommends that breastfeeding be discontinued during baricitinib therapy.

Maternal / infant drug levels

No information is available on the use of baricitinib during breastfeeding. Until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. The manufacturer recommends that breastfeeding be discontinued during baricitinib therapy.

Possible effects of Baricitinib on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Baricitinib

(Rheumatoid Arthritis) Auranofin, Gold Sodium Thiomalate, Hydroxychloroquine, Infliximab, Methotrexate, Penicillamine, Sulfasalazine.

List of References

Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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