The Basics
What is Ceftazidime and Avibactam?
cephalosporin antibiotics that treat complicated infections in many different parts of the body (eg, stomach, kidneys) as well as hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia
Brand names for Ceftazidime and Avibactam
Avycaz
How Ceftazidime and Avibactam is classified
Anti-Infective Agents, Antibacterial Agents, Cephalosporins
Ceftazidime and Avibactam During Pregnancy
Ceftazidime and Avibactam pregnancy category
Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Ceftazidime and Avibactam while pregnant
N/A
Taking Ceftazidime and Avibactam While Breastfeeding
What are recommendations for lactation if you're taking Ceftazidime and Avibactam?
Limited information indicates that ceftazidime produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Avibactam has not been studied in nursing mothers. Occasionally disruption of the infant’s gastrointestinal flora, resulting in diarrhea or thrush have been reported with cephalosporins, but these effects have not been adequately evaluated. Ceftazidime-avibactam is acceptable in nursing mothers.
Maternal / infant drug levels
Limited information indicates that ceftazidime produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Avibactam has not been studied in nursing mothers. Occasionally disruption of the infant’s gastrointestinal flora, resulting in diarrhea or thrush have been reported with cephalosporins, but these effects have not been adequately evaluated. Ceftazidime-avibactam is acceptable in nursing mothers.
Possible effects of Ceftazidime and Avibactam on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Ceftazidime and Avibactam
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Blanco JD, Jorgensen JH, Castaneda YS et al. Ceftazidime levels in human breast milk. Antimicrob Agents Chemother. 1983;23:479-80. PMID: 6342531
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
