The Basics

What is Ceftolozane and Tazobactam?

A cephalosporin antibiotic used to treat a variety of bacterial infections.

Brand names for Ceftolozane and Tazobactam

Zerbaxa

How Ceftolozane and Tazobactam is classified

Anti-Infective Agents, Antibacterial Agents, Cephalosporins

Ceftolozane and Tazobactam During Pregnancy

Ceftolozane and Tazobactam pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Ceftolozane and Tazobactam while pregnant

N/A

Taking Ceftolozane and Tazobactam While Breastfeeding

What are recommendations for lactation if you're taking Ceftolozane and Tazobactam?

No information is available on the clinical use of ceftolozane-tazobactam during breastfeeding. No serious adverse effects have been reported for other cephalosporin antibiotics during breastfeeding. Occasionally disruption of the infant’s gastrointestinal flora, resulting in diarrhea or thrush have been reported with cephalosporins, but these effects have not been adequately evaluated. Ceftolozane-tazobactam is acceptable in nursing mothers.

Maternal / infant drug levels

No information is available on the clinical use of ceftolozane-tazobactam during breastfeeding. No serious adverse effects have been reported for other cephalosporin antibiotics during breastfeeding. Occasionally disruption of the infant’s gastrointestinal flora, resulting in diarrhea or thrush have been reported with cephalosporins, but these effects have not been adequately evaluated. Ceftolozane-tazobactam is acceptable in nursing mothers.

Possible effects of Ceftolozane and Tazobactam on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Ceftolozane and Tazobactam

None listed

List of References

Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed

Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.

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